In this brief report we describe a case of juvenile Basedow disease associated which exophthalmus and treated with deflazacort and methimazole on the basis of its immune origin (as confirmed by the presence of high levels of antimicrosomal antibodies). After only two months of therapy, we already noted a definite reduction of the exophthalmus and normalization of the thyroid hormone parameters with disappearance of the antimicrosomal antibodies.

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