Multi-slit equipment is a new experimental apparatus that can measure the input-output characteristics of a CR (computed radiography) system with limited influence of the fading effect. Kimoto et al. recently proposed a new type of multi-slit apparatus in which the multi-slit setup, the insertion region of the phosphor plate, and plate shielding are integrated to create a single handy-type item (an all-in-one type multi-slit apparatus). However, some problems remained unsolved. The aims of this study were to devise a setup for application to high tube voltage conditions, and to improve the all-in-one type multi-slit equipment so as to correct the heel effect. We examined the capabilities of our improved multi-slit equipment using diagnostic X-ray apparatus and found that it can obtain input-output characteristics with 5% accuracy for tube voltages of 40-140 kV and SID (source to image receptor distances) of 50-200 cm.
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http://dx.doi.org/10.6009/jjrt.2014_jsrt_70.9.867 | DOI Listing |
Phys Med
August 2024
Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Purpose: The purpose of this study is to investigate the dosimetric characteristics of a collimator for minibeam radiotherapy (MBRT) with film dosimetry and Monte Carlo (MC) simulations. The outcome of MBRT with respect to conventional RT using a glioma preclinical model was also evaluated.
Methods: A multi-slit collimator was designed to be used with commercial small animal irradiator.
Phys Med Biol
November 2021
Department of Engineering Physics, Tsinghua University, Beijing 100084, People's Republic of China.
For certain radionuclides that decay through emitting two or more gamma photons consecutively within a short time interval-called cascade gamma-rays, the location where a radiopharmaceutical molecule emits cascade gamma-rays can be identified through coincidence detection of the photons. If each cascade photon is detected through a collimation mechanism, the location of the molecule can be inferred from the intersection of the back-projections of the two photons.In this work, we report the design and evaluation of a three-dimensional stationary imager based on this concept for imaging distributions of cascade-emitting radionuclides in radiopharmaceutical therapy.
View Article and Find Full Text PDFIEEE Trans Med Imaging
March 2021
CT scan by use of a beam-filter placed between the x-ray source and the patient allows a single-scan low-dose dual-energy imaging with a minimal hardware modification to the existing CT systems. We have earlier demonstrated the feasibility of such imaging method with a multi-slit beam-filter reciprocating along the direction perpendicular to the CT rotation axis in a cone-beam CT system. However, such method would face mechanical challenges when the beam-filter is supposed to cooperate with a fast-rotating gantry in a diagnostic CT system.
View Article and Find Full Text PDFPhys Med Biol
December 2020
Department of Engineering Physics, Tsinghua University, Beijing 100084, People's Republic of China.
Helical CT has been widely used in clinical diagnosis. In this work, we focus on a new prototype of helical CT, equipped with sparsely spaced multidetector and multi-slit collimator (MSC) in the axis direction. This type of system can not only lower radiation dose, and suppress scattering by MSC, but also cuts down the manufacturing cost of the detector.
View Article and Find Full Text PDFSci Rep
November 2019
Centre for Medical and Radiation Physics, University of Wollongong, Wollongong, 2522, Australia.
Microbeam Radiation Therapy (MRT) is an emerging cancer treatment modality characterised by the use of high-intensity synchrotron-generated x-rays, spatially fractionated by a multi-slit collimator (MSC), to ablate target tumours. The implementation of an accurate treatment planning system, coupled with simulation tools that allow for independent verification of calculated dose distributions are required to ensure optimal treatment outcomes via reliable dose delivery. In this article we present data from the first Geant4 Monte Carlo radiation transport model of the Imaging and Medical Beamline at the Australian Synchrotron.
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