AI Article Synopsis
- Primary mediastinal tumors are rare and can include various types, such as lymphoma and thymoma, along with less common forms.
- A case involved a patient with a solitary mediastinal mass causing breathing difficulties, diagnosed as melanoma through a CT-guided biopsy, without any external skin lesions.
- The case highlights the rarity of melanoma presenting solely in the mediastinum and emphasizes the importance of identifying BRAF mutations for potential treatment options.
Article Abstract
Introduction: Primary mediastinal tumors are rare diseases including a broad spectrum of pathologies ranging from the well-known, such as lymphoma, thymoma or germ-line tumors to some very unusual presentations.
Case Report: We describe a solitary mediastinal mass compressing the bronchial and vascular system in a patient suffering from chronic dyspnea. Diagnosis, obtained by means of a CT-guided biopsy, was a melanoma without any sign of a primary cutaneous lesion which harbored the BRAF V600E mutation.
Conclusions: An exclusive mediastinal presentation of a malignant melanoma is exceptional and, in the context of BRAF mutation needs to be considered and diagnosed given the potential therapeutic impact.
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| http://dx.doi.org/10.1016/j.rmr.2013.11.004 | DOI Listing |
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