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An immunology primer for computational modelers. | LitMetric

An immunology primer for computational modelers.

J Pharmacokinet Pharmacodyn

Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA,

Published: October 2014

The immune system is designed to protect an organism from infection and damage caused by a pathogen. A successful immune response requires the coordinated function of multiple cell types and molecules in the innate and adaptive immune systems. Given the complexity of the immune system, it would be advantageous to build computational models to better understand immune responses and develop models to better guide the design of immunotherapies. Often, researchers with strong quantitative backgrounds do not have formal training in immunology. Therefore, the goal of this review article is to provide a brief primer on cellular immunology that is geared for computational modelers.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850904PMC
http://dx.doi.org/10.1007/s10928-014-9384-yDOI Listing

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