We describe an exceptional case of life-threatening group A Escherichia coli-induced purpura fulminans. Genotyping of common polymorphisms in genes involved in innate immunity or coagulation did not reveal known susceptibility to such a manifestation. Genetic analysis of the strain revealed an unusual conserved virulence plasmidic region, pointing out its potential virulence.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313347PMC
http://dx.doi.org/10.1128/JCM.01362-14DOI Listing

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