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Effects of baclofen on swallow motor pattern.
Front Neurol
February 2025
Department of Speech Language and Hearing Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.
Baclofen is a GABA receptor agonist used clinically to manage spasticity. It has also been associated with increased duration of mechanical ventilation and rates of aspiration pneumonitis. We hypothesized that baclofen would impair pharyngeal swallow, a vital airway protective reflex.
View Article and Find Full Text PDFContext: Some studies suggests that mind-body therapies may be helpful for people with multiple sclerosis (PwMS) for symptom management. PwMS have reported benefits from Tension and Trauma Releasing Exercises (TRE); however, only limited research exists on the potential benefits of TRE.
Objective: The study intended to determine whether an eight-week intervention of Tension and Trauma Releasing Exercises (TRE), a mind-body therapy, could primarily reduce fatigue and secondarily decrease other MS-related symptoms and to explore new, experimental outcome measures-sleep, hand motor function, gait function, cognitive function, or mood-for use in future research on TRE for PwMS.
A Modified Scoping Review of Interventions for Global Post Stroke Spasticity.
Toxicon
March 2025
Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, USA.
Purpose: Stroke is a major global health concern, and post-stroke spasticity (PSS) can severely impair mobility and quality of life. This modified scoping review synthesizes the most current evidence up to 2024 for interventions targeting PSS, employing GRADE methodology and a packed bubble chart adapted from the Evidence Alert Traffic Light System to rigorously evaluate the state of evidence to assist global healthcare professionals and policymakers in developing context-sensitive strategies that are both effective and feasible within their specific healthcare environments.
Methods: From a pool of 2,420 studies, 53 met our inclusion criteria and were subjected to a detailed analysis, representing 44 distinct interventions.
Evaluation of Spasticity Changes during Manual Hand Therapy Based on sEMG Features.
Annu Int Conf IEEE Eng Med Biol Soc
July 2024
Manual therapy has been extensively utilized in the clinical management of hand spasticity. Clinicians face challenges in accurately evaluating spasticity during manual therapies due to its dynamic changes, resulting in a heavy reliance on therapists' experience for assessing and adjusting the therapy process. Currently, the Modified Ashworth Scale (MAS) and surface electromyography (sEMG) have been widely used to evaluate spasticity.
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