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http://dx.doi.org/10.3747/pdi.2013-00148 | DOI Listing |
Cureus
November 2024
Department of Nephrology, Nagasaki University Hospital, Nagasaki, JPN.
A 46-year-old woman on peritoneal dialysis (PD) had cloudy peritoneal dialysis effluent that had persisted for 10 days by the time she visited our hospital. The white blood cell count in the effluent was elevated to 1500/μL, leading to a diagnosis of peritoneal dialysis-associated peritonitis. The effluent cleared within two days with treatment using cefazolin and ceftazidime, and the white blood cell count dropped to 0/μL by day 6.
View Article and Find Full Text PDFDrug Des Devel Ther
June 2020
Drug Discovery Research, Wockhardt Research Centre, Aurangabad, India.
Levonadifloxacin and its prodrug alalevonadifloxacin are novel broad-spectrum anti-MRSA agents belonging to the benzoquinolizine subclass of quinolone, formulated for intravenous and oral administration, respectively. Various in vitro and in vivo studies have established their antimicrobial spectrum against clinically significant Gram-positive, Gram-negative, atypical, and anaerobic pathogens. The potent activity of levonadifloxacin against MRSA, quinolone-resistant , and hetero-vancomycin-intermediate strains is an outcome of its well-differentiated mechanism of action involving preferential targeting to DNA gyrase.
View Article and Find Full Text PDFJ Infect Chemother
December 2019
Department of Nephrology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, Japan.
A-26-year-old man was admitted to our hospital with diffuse abdominal pain, nausea, and vomiting. He had a history of malignant nephrosclerosis, for which he had been receiving peritoneal dialysis (PD) for the past 14 months. His PD effluent was cloudy and turbid (white blood cell count, 10,528/μL; neutrophils 95.
View Article and Find Full Text PDFCase Rep Nephrol
December 2018
Program Director, Internal Medicine Residency, St Agnes Medical Center, Fresno, CA, USA.
Peritonitis is a very serious complication encountered in patients undergoing peritoneal dialysis and healthcare providers involved in the management should be very vigilant. Gram-positive organisms are the frequent cause of peritonitis compared to gram-negative organisms. There has been recognition of peritonitis caused by uncommon organisms because of improved microbiological detection techniques.
View Article and Find Full Text PDFRev Esp Quimioter
June 2016
Sara Hernández Egido, Complejo Asistencial Universitario de Salamanca Paseo de San Vicente nº 58-182 C.P. 37007 Salamanca, Spain.
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