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Analysis of risk factors for vascular cognitive impairment in patients with cerebral infarction. | LitMetric

Analysis of risk factors for vascular cognitive impairment in patients with cerebral infarction.

Cell Biochem Biophys

Department of Neurology, The Central Hospital of Xuzhou, No. 199 Jiefang South Road, Xuzhou, 221009, China,

Published: March 2015

AI Article Synopsis

  • - The study explored risk factors for vascular cognitive impairment (VCI) in patients who had a cerebral infarction, analyzing data from 300 participants.
  • - Important associations with VCI were found for factors like age, glycosylated hemoglobin, atrial fibrillation, blood pressure, homocysteine, and HS-CRP through single factor analysis.
  • - The multivariate logistic regression identified age, glycosylated hemoglobin, blood pressure, homocysteine, and HS-CRP as independent risk factors for VCI, suggesting they can help predict cognitive impairment in these patients.

Article Abstract

This study aimed to identify risk factors for vascular cognitive impairment (VCI) in cerebral infarction patients. Associations between VCI and age, gender, blood pressure, lipid levels, glycosylated hemoglobin, atrial fibrillation, tobacco smoking, alcohol consumption, homocysteine (Hcy), and High-Sensitivity C-Reactive Protein (HS-CRP) were evaluated in patients with cerebral infarction (n = 300) using single factor analysis and multivariate logistic regression analysis. By single factor analysis, the age, glycosylated hemoglobin, atrial fibrillation, blood pressure, Hcy, HS-CRP, tobacco smoking, and alcohol consumption were significantly associated with VCI in these patients. By multivariate logistic regression analysis, the age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP were revealed as independent risk factors. The age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP can serve as predictive factors for VCI in patients with cerebral infarction.

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Source
http://dx.doi.org/10.1007/s12013-014-0246-4DOI Listing

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