Positive ECT results were found in 29 out of 70 patients (41%) tested for suspected denture sore mouth syndrome. 11 of them reacted to nickel (16%), 4 to benzoyl peroxide, 4 to mercury chloride, but only 3 out of 38 patients reacted to their own prosthetic material. A follow-up study covered a group of 31 patients with dentures. 20 of them had mechanical or material changes made, but only 4 because of ECT results (1 nickel, 1 benzoyl peroxide, 1 own prosthetic material). After elimination of the suspected allergen, these 4 patients showed improvement, but the symptoms did not completely clear. A similar beneficial effect was seen in 13 of the 20 patients, whose dentures were only mechanically adapted; but 6 out of 11 patients without any dental correction showed improvement, as well. Our results suggest that clinically relevant contact allergies are rare in patients with burning mouth syndrome. Mechanical, microbial, and psychic factors have to be taken into consideration, as well.

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