Responding to alarm systems which usually commit a number of false alarms and/or misses involves decision-making under uncertainty. Four laboratory experiments including a total of 256 participants were conducted to gain comprehensive insight into humans' dealing with this uncertainty. Specifically, it was investigated how responses to alarms/non-alarms are affected by the predictive validities of these events, and to what extent response strategies depend on whether or not the validity of alarms/non-alarms can be cross-checked against other data. Among others, the results suggest that, without cross-check possibility (experiment 1), low levels of predictive validity of alarms ( ≤ 0.5) led most participants to use one of two different strategies which both involved non-responding to a significant number of alarms (cry-wolf effect). Yet, providing access to alarm validity information reduced this effect dramatically (experiment 2). This latter result emerged independent of the effort needed for cross-checkings of alarms (experiment 3), but was affected by the workload imposed by concurrent tasks (experiment 4). Theoretical and practical consequences of these results for decision-making and response selection in interaction with alarm systems, as well as the design of effective alarm systems, are discussed.
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http://dx.doi.org/10.1080/00140139.2014.957732 | DOI Listing |
Microsyst Nanoeng
January 2025
Key Laboratory of Instrumentation Science and Dynamic Measurement Ministry of Education, North University of China, 030051, Taiyuan, China.
The alarming prevalence and mortality rates associated with cardiovascular diseases have emphasized the urgency for innovative detection solutions. Traditional methods, often costly, bulky, and prone to subjectivity, fall short of meeting the need for daily monitoring. Digital and portable wearable monitoring devices have emerged as a promising research frontier.
View Article and Find Full Text PDFHardwareX
March 2025
Industrial Design Engineering, Delft University of Technology, Delft, the Netherlands.
Negative Pressure Wound Therapy (NPWT) is a treatment that promotes healing of chronic wounds. Despite high prevalence of chronic wounds in Low- and Middle-Income Countries (LMICs), NPWT devices are not available nor affordable. This study aims to improve chronic wound care in LMICs by presenting the Wound Care (WOCA) system, designed for building, testing and use in LMICs.
View Article and Find Full Text PDFAsian J Med Humanit
January 2024
Faculté de Medicine, Université de Montréal, Montréal, Québec, Canada.
Objectives: The overall goal of this article is to show that denial is one of the greatest obstacles to good practical judgment and is therefore a major problem in clinical ethics by examining its cognitive structure and the challenges it poses for clinical ethics consultation and intervention. In addition to clinical examples, excerpts of verbatim from citizen forums on triage protocols will be used to illustrate the manifestations of denial in citizens when faced with difficult choices.
Case Presentation: The initial waves of the pandemic and the alarming resurgence of cases with the emergence of highly transmissible variants have created increased pressure on many healthcare systems around the world.
Virology
January 2025
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730000, China. Electronic address:
Porcine teschovirus (PTV) is a devastating virus that targets the central nervous system and led to great economic losses in Europe between the 1920s and 1960s. Since 1973, PTV variants with lower pathogenicity have been prevalent globally, whereas highly pathogenic PTV strains have rarely emerged. In 2022, diarrhea with high mortality occurred on a pig farm in Gansu China.
View Article and Find Full Text PDFExpert Opin Drug Deliv
January 2025
Drug Transport and Delivery Research Group, Department of Pharmacy, Faculty of Health Sciences, University of Tromsø The Arctic University of Norway, Tromsø, Norway.
Introduction: Liposomal hydrogels are novel drug delivery systems that comprise preformed liposomes incorporated in hydrogels destined for mostly localized drug therapy, herewith antimicrobial therapy. The formulation benefits from versatility of liposomes as lipid-based nanocarriers that enable delivery of various antimicrobials of different lipophilicities, and secondary vehicle, hydrogel, that assures better retention time of formulation at the infection site. Especially in an era of alarming antimicrobial resistance, efficient localized antimicrobial therapy that avoids systemic exposure of antimicrobial and related side effects is crucial.
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