Objectives: This study aims to establish if transfer distance impacts the outcome of ST-elevation myocardial infarction (STEMI) patients transferred to a percutaneous coronary intervention (PCI).
Background: Regional emergency care systems were designed to decrease delays in reperfusion of patients but the effect of transfer distance on outcome is less established.
Methods: We compare the characteristics and outcomes of STEMI patients transferred from a distance >25 miles (GT25) to those transferred from distances ≤25 miles (LT25) by utilizing data from a regional STEMI care network in the greater Washington DC area.
Results: Within the transferred patients (n=1065), 609 patients (57%) were transferred from GT25 (median distance 36 miles), while 456 (43%) were transferred from LT25 (median distance 13 miles). Most of the baseline characteristics between the groups were similar. Door-to-balloon (DTB) was defined as the time elapsed from the presentation to the center without PCI capability to flow restoration in the culprit artery. No differences were noted in the median DTB (GT25: 158min [122-213] vs. 149 [118-219]; p=0.5) or in in-hospital mortality (8% vs. 7.2%; p=0.617). By implementing the regional STEMI care network, a constant decrease in DTB was noted throughout its years of operation.
Conclusions: For STEMI patients presenting to a non-PCI capable center, a network care system for PCI mitigates the distance factor on DTB time. This is turn translates into comparable outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.carrev.2014.08.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cost-Effective Bioimpedance Spectroscopy System for Monitoring Syncytialization In Vitro: Experimental and Numerical Validation of BeWo Cell Fusion.
Micromachines (Basel)
December 2024
Department of Mechanical Engineering, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
The placenta plays a critical role in nutrient and oxygen exchange during pregnancy, yet the effects of medicinal drugs on this selective barrier remain poorly understood. To overcome this, this study presents a cost-effective bioimpedance spectroscopy (BIS) system to assess tight junction integrity and monolayer formation in BeWo b30 cells, a widely used model of the multinucleated maternal-fetal exchange surface of the placental barrier. Cells were cultured on collagen-coated porous membranes and treated with forskolin to induce controlled syncytialization.
View Article and Find Full Text PDFSorption of Platinum and Palladium on Polyethylene Microplastics in Natural Water.
Molecules
December 2024
Department of Analytical and Inorganic Chemistry, Faculty of Chemistry, University of Bialystok, Ciołkowskiego 1K, 15-245 Bialystok, Poland.
In this work, for the first time, the sorption behaviour of platinum and palladium on polyethylene microplastics (PE-MP) was studied. To simulate natural conditions, part of PE-MP was subjected to the ageing process in lake water under the influence of solar radiation. The original and aged PE-MP was characterised using elemental analysis, FT-IR, SEM-EDX, and nitrogen porosimetry methods.
View Article and Find Full Text PDFDevelopment and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease.
J Vasc Surg Cases Innov Tech
February 2025
Department of Health and Kinesiology, Purdue University, West Lafayette, IN.
Article Synopsis
- Individuals with symptomatic lower extremity peripheral artery disease (PAD) experience significant leg pain and reduced quality of life, with limited treatment options currently available.
- Emerging research shows that regular heat therapy (HT) might enhance cardiovascular and physical function in PAD patients, but practical, unsupervised HT methods for the elderly are lacking.
- A new portable leg HT system was developed for elderly patients, featuring safety mechanisms and tested for 12 weeks with positive results in terms of usability, safety, and improved clinical outcomes, including increased leg temperature and reduced blood pressure.
Stacked-ring aromaticity from the viewpoint of the effective number of π-electrons.
Chem Sci
December 2024
Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University Toyonaka Osaka 560-8531 Japan
In this study, we theoretically examined the mechanism of aromaticity induced in closely stacked cofacial π-dimers of 4π antiaromatic molecules, which is called stacked-ring aromaticity, in terms of the effective number of π-electrons ( ) and Baird's rule. High-precision quantum chemical calculations combined with a multi-configurational wavefunction analysis revealed that double-triplet [(TT)] and intermolecular charge-transfer (CT) electron configurations mix substantially in the ground state wavefunctions of cyclobutadiene and Ni(ii) norcorrole dimer models at small stacking distance (). Since the T configuration gives rise to two unpaired electrons, the remaining 4 - 2 π electrons still participate in the intramolecular conjugation, which can be interpreted as the origin of the aromaticity of each monomer.
View Article and Find Full Text PDFElectrical impedance-based tissue classification for bladder tumor differentiation.
Sci Rep
January 2025
Institute for System Dynamics, University of Stuttgart, Waldburgstr. 19, 70563, Stuttgart, Germany.
Including sensor information in medical interventions aims to support surgeons to decide on subsequent action steps by characterizing tissue intraoperatively. With bladder cancer, an important issue is tumor recurrence because of failure to remove the entire tumor. Impedance measurements can help to classify bladder tissue and give the surgeons an indication on how much tissue to remove.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!