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The Derivation of Acute and Chronic Environmental Quality Standards for Nickel in European Surface Waters: A Demonstrable need to follow scientific evidence.
Integr Environ Assess Manag
January 2025
NiPERA, Durham, North Carolina, USA.
Environmental Quality Standards (EQS) derived under the European Water Framework Directive are legally binding and enshrined in individual European Member State Country national legislation. These EQS are derived following well-established guidance documents. In 2013, EQS for nickel were derived for freshwaters to be protective against long and short-term exposures, at 4 and 34 µg L-1, respectively.
View Article and Find Full Text PDFRegular Use of Oral Nonsteroidal Anti-inflammatory Drugs in a Population of Polish Seniors: Findings from the PolSenior2 Cross-Sectional Survey.
Drugs Aging
January 2025
Department of Preventive Medicine and Education, Medical University of Gdansk, Gdańsk, Poland.
Introduction: Older adults represent a growing proportion of the general population. Nonsteroidal anti-inflammatory drugs (NSAIDs) constitute a group of medicines that are both necessary, owing to their anti-inflammatory, analgesic, and cardioprotective abilities, and potentially harmful, owing to their side effects.
Objectives: This study provides a comprehensive analysis of NSAID usage patterns among Polish adults aged 60 years and older.
The content and associated health risk assessment of toxic elements, micro-, and macrominerals in common carp, Wels catfish, and silver carp from the Danube River in Serbia.
Environ Geochem Health
January 2025
Military Health Department, Veterinary Service Centre, Ministry of Defence of Republic of Serbia, Crnotravska 17, 11000, Belgrade, Serbia.
Three fish species (common carp, Wels catfish, and silver carp) were collected from three locations along the Danube River in Serbia, and fish meat was analyzed for the content of toxic elements, micro- and macrominerals. Silver carp had the highest lead (Pb), arsenic (As), and cadmium (Cd) content, while Wels catfish had the highest level of mercury (Hg). Moreover, metal pollution index (MPI) ranged from 0.
View Article and Find Full Text PDFFollowing a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to provide an opinion on the safety of a change of the specifications of the authorised NF 'phytosterols/phytostanols' as a novel food (NF) pursuant to Regulation (EU) 2015/2283. This authorised NF concerns phytosterols extracted from plants and which may be presented as free sterols and stanols or esterified with food grade fatty acids. It has to contain less than 81% β-sitosterol, less than 35% β-sitostanol, less than 40% campesterol, less than 15% campestanol, less than 30% stigmasterol and less than 3% brassicasterol.
View Article and Find Full Text PDFInteractions of Oligodendrocyte Precursor Cells and Dopaminergic Neurons in the Mouse Substantia Nigra.
J Neurochem
January 2025
Institute for Physiology, University of Tübingen, Tübingen, Germany.
Parkinson's disease (PD) is a prevalent neurodegenerative disease caused by the death of dopaminergic neurons within the substantia nigra pars compacta (SNpc) region of the midbrain. Recent genomic and single cell sequencing data identified oligodendrocytes and oligodendrocyte precursor cells (OPCs) to confer genetic risk in PD, but their biological role is unknown. Although SNpc dopaminergic neurons are scarcely or thinly myelinated, there is a gap in the knowledge concerning the physiological interactions between dopaminergic neurons and oligodendroglia.
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