Objectives: To evaluate how chronic kidney disease (CKD) and diabetes mellitus (DM) influence in-hospital mortality in patients urgently admitted for acute heart failure (HF).
Methods: We used data from the Spanish "Minimum Basic Data Set" for 2006-2007 to evaluate clinical differences and crude mortality rates for patients having versus non-having CKD or DM. We tested pre-specified predictive factors of in-hospital mortality in a multivariate logistic regression model, which included age, sex, CKD, DM, acute respiratory failure, a modified Charlson Comorbidity Index-excluding CKD/DM- and a CKD × DM-interaction variable. p Values < 0.05 were considered significant.
Main Findings: A total of 275,176 episodes of acute HF were analyzed (47.9% male, mean age 76.2 ± 12.8 years). CKD patients (N = 25,174, 9.1%) were older (78.4 ± 10.1 vs. 76.0 ± 13.1 years; p < 0.001) and more frequently had coexisting medical conditions. DM patients (N = 88,994, 32.3%) more often had vascular risk factors and CKD (11.4% vs. 8.1%; p < 0.001). Overall in-hospital mortality rate for admitted HF patients was 10.4%. Mortality was lower for DM versus non-DM patients (9.2% vs. 11.0%; p < 0.001), but higher for CKD versus non-CKD patients (14.1% vs. 10.0%; p < 0.001). No interaction effect was found between CKD and DM on survival for a HF episode (odds ratio; OR = 1.01, 95% CI: 0.91-1.10; p for interaction = 0.73). DM remained protective (OR = 0.85, 95% CI: 0.82-0.87; p < 0.001), while CKD was associated with increased mortality (OR = 1.46, 95% CI: 1.39-1.53; p < 0.001).
Conclusions: In patients urgently admitted for HF, the association of CKD with higher in-hospital mortality was homogeneous irrespectively of the absence or presence of DM.
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http://dx.doi.org/10.3109/0886022X.2014.958974 | DOI Listing |
Sci Rep
December 2024
The School of Nursing, Fujian Medical University, No. 1 Xuefu North Road, Fuzhou, 350122, Fujian, China.
Diabetes Mellitus combined with Mild Cognitive Impairment (DM-MCI) is a high incidence disease among the elderly. Patients with DM-MCI have considerably higher risk of dementia, whose daily self-care and life management (i.e.
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December 2024
Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia.
Excessive daytime sleepiness is a common finding among type 2 diabetes mellitus patients. However there is scarce data that shows the magnitude of excessive daytime sleepiness, & its association with type 2 diabetes mellitus. Hence, the study aimed to assess the prevalence of excessive daytime sleepiness and its associated factors among type 2 diabetes mellitus patients at Wolkite University Specialized Hospital.
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December 2024
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
No study has examined the association between dietary insulin load (DIL) and insulin index (DII) with developing gestational diabetes mellitus (GDM) during pregnancy. This study aimed to investigate the association between DIL and DII and risk of GDM in a group of pregnant women in Iran. In this prospective cohort study, 812 pregnant in their first trimester were recruited and followed.
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December 2024
Department of International Medical, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China.
Background: Diabetes mellitus (DM) and arthritis are prevalent conditions worldwide. The intricate relationship between these two conditions, especially in the context of various subtypes of arthritis, remains a topic of interest.
Objective: To investigate the relationship between diabetes and arthritis, with a focus on Rheumatoid Arthritis (RA), using data from the National Health and Nutrition Examination Survey (NHANES) and Mendelian Randomization (MR) analysis.
Small
December 2024
State Key Laboratory of Oral Diseases, School of Chemical Engineering, National Center for Stomatology & National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, 610041, China.
Intractable implant-associated infections (IAIs) are the primary cause of prosthetic implant failure, particularly in the context of diabetes mellitus. There is an urgent need to design and construct versatile engineered implants integrated with cascade amplification therapeutic modality to significantly improve the treatment of diabetic IAIs. To address this issue, a multi-functional MXene/AgPO@glucose oxidase bio-heterojunction enzyme (M/A@GOx bio-HJzyme) coating is developed, which is decorated with an inert sulfonated polyetheretherketone implant (SP-M/A@G) via hydrothermal treatment and layered deposition.
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