The authors studied some serum indices of protein and electrolyte metabolism (total protein, protein fraction, serum calcium, ionized calcium, phosphorus, potassium, sodium, osmolality, Ca/P ratio) in 26 clinically healthy children, aged fro 7 to 10, with clinically diagnosed dysplasia (hypoplasia or hypomineralization) of the permanent teeth. The mean values of the single biochemical parameters for both groups of children remain within referent limits of the respective indices for childhood, and their comparison established no statistically significant differences (p greater than 0.05). That provided grounds the authors to associate with the opinion that enamel defects, localized on a restricted part of the clinical crown of a symmetric group of teeth, could be "markers" for disorders in protein and mineral metabolism only during a certain time period coinciding with the active phases of odontogenesis. The absence of lasting changes in those two metabolisms determined the trends of the secondary prophylaxis--caries-prophylactic measures aiming at the avoidance of complications.

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