AI Article Synopsis
- Crouzon's syndrome (CS) is a rare genetic disorder caused by mutations in the FGFR2 gene, accounting for 4.8% of craniosynostosis cases.
- It leads to various physical features including cranial deformities, midface underdevelopment, and dental issues, with severity ranging from mild to severe.
- A case study is presented involving an 11-year-old boy diagnosed with Crouzon's syndrome.
Article Abstract
Crouzon's syndrome (CS) is a rare autosomal dominant condition with multiple mutations of the fibroblast growth factor receptor (FGFR2) gene, which accounts for 4.8% of all cases of craniosynostosis. It is characterized by premature closure of cranial sutures, cranial deformities, midface hypoplasia, relative mandibular prognathism, hypertelorism, proptosis, strabismus and short upper lip, crowding of teeth, pseudocleft or sometimes cleft palate and other associated abnormalities. The CS can vary in severity from mild presentation to severe forms involving multiple cranial sutures. We report a case of CS in 11-year-old boy. How to cite this article: Kumar GR, Jyothsna M, Ahmed SB, Lakshmi KS, Crouzon's Syndrome: A Case Report. Int J Clin Pediatr Dent 2013;6(1):33-37.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034637 | PMC |
| http://dx.doi.org/10.5005/jp-journals-10005-1183 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!