Photodynamic therapy (PDT) is presented as a promising antimicrobial therapy that can eliminate microorganisms present in endodontic infections. This treatment is based on the use of a nontoxic photosensitizing agent followed by irradiation of a resonant light source being capable of generating highly reactive species that are harmful to microorganisms. The purpose of this paper is to review the dental literature about the main factors that encompass the use of PDT combined with endodontic treatment for decontamination of the root canal system. A literature search was performed using the following index databases: PubMed, ISI Web of Knowledge and MedLine, between 2000 and 2014, looking for studies regarding antimicrobial action of PDT and its application to endodontic therapy. It was observed that despite numerous promising results, it is still necessary to establish different parameters so that PDT can be used with maximum effectiveness in eliminating microorganisms that cause endodontic infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144146 | PMC |
| http://dx.doi.org/10.4103/1305-7456.137662 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of antibacterial efficacy of propolis as an intercanal medicament against (a randomized controlled in vitro study).
Heliyon
January 2025
Department of Restorative Dentistry and Endodontic, Faculty of Dentistry, Damascus University, Damascus, Syria.
Background: () is one of the microorganisms responsible for the pathology of root canals. We aimed in this study to determine the efficacy of two different pastes (calcium hydroxide combined with saline and calcium hydroxide combined with propolis) as a dressing material in eradicating from infected root canals.
Methods: Twenty extracted single-rooted and single-canalled first premolars randomly distributed into two equal groups of 10 teeth each.
Microbial Dynamics in Endodontic Pathology-From Bacterial Infection to Therapeutic Interventions-A Narrative Review.
Pathogens
December 2024
Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Endodontic infection is a penetration of microorganisms into the dental pulp. Bacteria are the most common entities that induce an infection. This state is associated with significant pain and discomfort.
View Article and Find Full Text PDFComparative in Vitro Study on the Antimicrobial Efficacy of Endodontic Sealers Against Common Oral Pathogens.
Dent J (Basel)
December 2024
Department of Odontology and Oral Pathology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, Romania.
: Microorganisms are the leading cause of infections in the root canal system, contributing to the failure of endodontic treatments. This in vitro study aimed to compare the antimicrobial effects of four different endodontic sealers: Endomethasone N (Septodont, Saint Maur-des-Fossés, France), Sealapex (Kerr Corporation, Orange, CA, USA), AH Plus Jet (Dentsply DeTrey GmbH, Konstanz, Germany), and MTA Fillapex (Angelus, Londrina, Brazil). : The sealers were tested against common oral pathogens, including Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Candida albicans, and Streptococcus mutans, using the agar diffusion method.
View Article and Find Full Text PDFExploring the multifaceted roles of metal-organic frameworks in ecosystem regulation.
J Mater Chem B
January 2025
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Achieving microecological balance is a complex environmental challenge. This is because the equilibrium of microecological systems necessitates both the eradication of harmful microorganisms and preservation of the beneficial ones. Conventional materials predominantly target the elimination of pathogenic microorganisms and often neglect the protection of advantageous microbial species.
View Article and Find Full Text PDFMicrobiological and toxicity analyses of the synthetic polymer polyhexamethylene guanidine hydrochloride against endodontic microorganisms.
Braz J Microbiol
January 2025
Department of Postgraduate Program in Animal Science, University of Franca (UNIFRAN), Av. Dr. Armando Salles Oliveira, 201, Parque Universitário, Franca, SP, CEP 14.404-600, Brazil.
Failures in endodontic treatments are common due to microbial resistance in the pulp canal. The study evaluated the in vitro activity of polyhexamethylene guanidine hydrochloride (PHMGH) against endodontic strains, as well as in vivo toxicity. Using minimum inhibitory concentration and minimum bactericidal concentration techniques, PHMGH was effective against all microorganisms, even at low concentrations.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!