Purpose: Acute kidney injury (AKI) is associated with adverse outcomes after acute ST elevation myocardial infarction (STEMI). The recently proposed AKI network (AKIN) suggested modifications to the consensus classification system for AKI known as the risk, injury, failure, loss, end-stage (RIFLE) criteria. The aim of the current study was to compare the incidence and mortality (early and late) of AKI diagnosed by RIFLE and AKIN criteria in the STEMI patients undergoing primary percutaneous intervention (PCI).
Methods: We retrospectively studied 1,033 consecutive STEMI patients undergoing primary PCI. Recruited patients were admitted between January 2008 and November 2012 to the cardiac intensive care unit with the diagnosis of acute STEMI. We compared the utilization of RIFLE and AKIN criteria for the diagnosis, classification, and prediction of mortality.
Results: The AKIN criteria allowed the identification of more patients as having AKI (9.6 vs. 3.9 %, p < 0.001) and classified more patients with stage 1 (risk in RIFLE) (7.6 vs. 1.9 %, p < 0.001) compared with the RIFLE criteria. Mortality was higher in AKI population defined by either RIFLE (46.3 vs. 6.8 %, OR 11.9, 95 % CI 6.15-23.1; p < 0.001) or AKIN (29 vs. 6.1 %; OR 6.3, 95 % CI 3.8-10.4; p < 0.001) criteria. In a multivariable logistic regression model, AKI defined with both RIFLE and AKIN was an independent predictor of both 30-day and up to 5-year all-cause mortality. However, there was no significant statistical difference in the risk provided by these two scoring systems.
Conclusions: AKIN criteria are more sensitive in defining AKI compared with the RIFLE criteria in STEMI. However, no difference exists in the mortality risk provided by these two scoring systems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11255-014-0827-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Reduction of vancomycin-associated acute kidney injury with montelukast.
J Infect Dis
January 2025
Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy; Houston, Texas, 77204, United States of America.
Background: Vancomycin ranks amongst the most utilized antimicrobial agents in the treatment of serious β-lactam-resistant Gram-positive infections, but its use has been associated with nephrotoxicity. Reduction of acute kidney injury (AKI) has been reported in pre-clinical models with adjuvant montelukast. The purpose of the study was to ascertain if montelukast was associated with a reduction in the prevalence of vancomycin-associated AKI.
View Article and Find Full Text PDFCardiorespiratory demands of firearms training instruction and 15m shuttle tests in British law enforcement.
PLoS One
January 2025
Division of Surgery & Interventional Science, Institute of Sport Exercise and Health, University College London, London, United Kingdom.
Objectives: Law enforcement agencies require minimum fitness standards to safeguard their officers and training staff. Firearms instructors (FI) are expected to maintain the same standards as their operational counterparts. This study aimed to quantify the daily physiological demands placed on FI.
View Article and Find Full Text PDFBlended police firearms training improves performance in shoot/don't shoot scenarios: a systematic replication with police cadets.
Front Psychol
December 2024
Department of Business Studies, Westfälische Hochschule, Gelsenkirchen, Germany.
Senior police officers' tactical gaze control and visual attention improve with an individual video-based police firearms training. To validate the efficacy of said intervention training, a previous experiment was systematically replicated with a sample of = 52 second-year police cadets. Participants were randomly assigned to the intervention training that focused on situational awareness, tactical gaze control, and visual attention, or an active control training that addressed traditional marksmanship skills.
View Article and Find Full Text PDFGunshots detection, identification, and classification: Applications to forensic science.
Sci Justice
November 2024
Benxi Judicial Appraisal Institution, Benxi Liaoning, China.
ce proliferation of audio sensors in surveillance, smartphones, and numerous devices has made gunshots-based event detection and forensic analysis critical for prompt police action and crime scene reconstruction. This paper initiates an analysis of the acoustic characteristics of gunshots and the variables affecting them, assessing their applicability and limitations in forensic science. It follows with a comprehensive review of existing literature on gunshots detection, identification, and classification technologies, detailing the critical components of machine learning applications, including dataset construction, feature extraction, and classifier selection.
View Article and Find Full Text PDFRobot-assisted partial nephrectomy of multiple tumors: a multicenter analysis.
Minerva Urol Nephrol
November 2024
Hannover Medical School, Department of Urology and Urological Oncology, Hannover, Germany -
Article Synopsis
- - The study aimed to analyze factors affecting postoperative renal function (PRF) following robot-assisted partial nephrectomy for patients with multiple kidney tumors, using data from 132 surgeries and assessing both patient and surgical influences on outcomes.
- - Key findings included that most patients had two tumors, the average surgery lasted 175 minutes, and that the majority of surgeries met trifecta criteria, indicating successful outcomes in terms of cancer control, renal preservation, and complications.
- - Factors such as warm ischemia time, body mass index (BMI), and preoperative kidney function were found to impact kidney function loss post-surgery, with BMI and comorbidities being significant predictors of acute kidney injury during hospitalization.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!