Background: The patient-specific guide for total knee arthroplasty (TKA) is created from the data provided by magnetic resonance imaging (MRI) or computed tomography (CT) scans. It remains unknown which imaging technology is suitable for the patient-specific guide. The purpose of this study was to compare the accuracy of implant positioning and operative times between the two types of patient-specific guides for TKA.
Methods: Forty arthritic knees were divided into two treatment groups using MRI-based (PS-MRI group) or CT-based (PS-CT group) patient-specific guides in this prospective, comparative study. The guide in the PS-MRI group had a cutting slot, whereas that in the PS-CT group only had a pin locator. The operative times were compared between the two groups. The angular error and number of outliers (deviations >3°) of the implant position using pre- and postoperative CT were investigated in both groups.
Results: The mean operative time was significantly shorter in the PS-MRI group (109.2 ± 16.5 min) than in the PS-CT group (129.5 ± 19.4 min) (p<0.001). There were no significant differences in the accuracy of the implant position regarding the coronal, sagittal, and axial planes between the groups (p>0.05).
Conclusions: To reduce the operative time, guides with additional functions, such as cutting and positioning, should be used. Both CT- and MRI-based-guides would result in the same accuracy in three planes but high inaccuracy in the sagittal plane. The use of patient-specific guide based on MRI might not be cost-effective.
Level Of Evidence: level 2.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.knee.2014.08.015 | DOI Listing |
Biomech Model Mechanobiol
December 2024
Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complex Systems, Peking University, Beijing, 100871, China.
Central blood pressure (cBP) is considered a superior indicator of cardiovascular fitness than brachial blood pressure (bBP). Even though bBP is easy to measure noninvasively, it is usually higher than cBP due to pulse wave amplification, characterized by the gradual increase in peak systolic pressure during pulse wave propagation. In this study, we aim to develop an individualized transfer function that can accurately estimate cBP from bBP.
View Article and Find Full Text PDFSTAR Protoc
December 2024
Institute Pharmaceutical Biology/DCAL, Goethe-University, 60438 Frankfurt am Main, Germany. Electronic address:
KMT2A rearrangements are associated with a poor clinical outcome in infant, pediatric, and adult acute lymphoblastic and myeloid leukemia. Here, we present a protocol to reconstruct chromosomal translocations with different partner genes of KMT2A in vitro. We describe steps for patient-specific single guide RNA (sgRNA) design, optimized sgRNA in vitro transcription, detailed purification of hematopoietic stem and progenitor cells (HSPCs) from umbilical cord blood (UCB), and CRISPR-Cas9 editing of the test cell line K562 as well as UCB HSPCs.
View Article and Find Full Text PDFMed Phys
December 2024
Department of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Background: Manual contour corrections during fractionated magnetic resonance (MR)-guided radiotherapy (MRgRT) are time-consuming. Conventional population models for deep learning auto-segmentation might be suboptimal for MRgRT at MR-Linacs since they do not incorporate manual segmentation from treatment planning and previous fractions.
Purpose: In this work, we investigate patient-specific (PS) auto-segmentation methods leveraging expert-segmented planning and prior fraction MR images (MRIs) to improve auto-segmentation on consecutive treatment days.
BMC Anesthesiol
December 2024
Unidad de Inteligencia Artificial, Fundación Valle del Lili, Cra 98 Num.18-49, Cali, 760032, Valle del Cauca, Colombia.
Artificial Intelligence (AI), especially Machine Learning (ML), has developed systems capable of performing tasks that require human intelligence. In anesthesiology and other medical fields, AI applications can improve the precision and efficiency of daily clinical practice, and can also facilitate a personalized approach to patient care, which can lead to improved outcomes and quality of care. ML has been successfully applied in various settings of daily anesthesiology practice, such as predicting acute kidney injury, optimizing anesthetic doses, and managing postoperative nausea and vomiting.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Minimally invasive surgical techniques, such as MR-guided laser interstitial thermal therapy (LITT), have emerged as promising alternatives to open disconnective surgeries in drug-resistant epilepsy (DRE). This review synthesizes current literature on the application of LITT for corpus callosal disconnection and functional hemispheric disconnection. Studies highlight LITT's effectiveness for achieving seizure control and functional outcomes, often with reduced complications compared to traditional open procedures.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!