Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol.

Huai-Rong Zhang Yin-Zhu Wang Mei-Sheng Wu Qiu-Mei Feng Hai-Wei Shi Hong-Yuan Chen Jing-Juan Xu

Chem Commun (Camb)

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.

Published: October 2014

A novel visual electrochemiluminescence (ECL) analysis strategy for detection of telomerase activity is reported on a microarray chip, with G-quadruplex deoxyribozyme (DNAzyme) and luminol modified Au nanoparticles (NPs) as double-catalytic amplification labels.

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http://dx.doi.org/10.1039/c4cc06302c	DOI Listing

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