Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Endometrioid tubal intraepithelial neoplasia (E-TIN): case report & literature review.
J Mol Histol
November 2024
Department of Histopathology and Cytopathology, Cotman Centre, Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UB, UK.
An endometrioid carcinogenic pathway of the fallopian tube with possible potential precursors including type II SCOUTs (secretory cell outgrowths) and E-TIN (endometrioid tubal intraepithelial neoplasia) has been recently documented. We report an incidental focus of E-TIN identified in a hysterectomy specimen for Grade 1 endometrioid type endometrial carcinoma. The lesion was present at the fimbriated end of left fallopian tube involving 1 plica.
View Article and Find Full Text PDFPrimary desmoplastic small round cell tumour of the prostate.
J Clin Pathol
December 2024
Department of Pathology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China
Article Synopsis
- Desmoplastic small round cell tumour (DSRCT) is a rare and aggressive soft-tissue sarcoma noted for its specific genetic characteristics, predominantly occurring in the abdominal cavity.
- While primary DSRCTs in the male genital system are extremely uncommon, this study presents two unique cases of primary DSRCT found in the prostate.
- The cases illustrated distinct morphological features and immunohistochemical profiles, expanding knowledge on the distribution of DSRCT and emphasizing its potential presence in prostate cancer diagnoses.
Editorial Comment to Histological parameters and stromal desmoplastic status affecting accurate diagnosis of extraprostatic extension of prostate cancer using multi-parametric magnetic resonance imaging.
Int J Urol
May 2024
Department of Urology, Tokai University School of Medicine, Kanagawa, Japan.
Histological parameters and stromal desmoplastic status affecting accurate diagnosis of extraprostatic extension of prostate cancer using multi-parametric magnetic resonance imaging.
Int J Urol
May 2024
Department of Radiology, National Defense Medical College, Tokorozawa, Saitama, Japan.
Objective: To investigate the clinicopathological factors affecting discrepancies between multi-parametric magnetic resonance imaging (mpMRI) and histopathological evaluation for diagnosis of extraprostatic extension (EPE) of prostate cancer.
Methods: One hundred-and-three lesions from 96 cases with suspected EPE on preoperative mpMRI, of which 60 and 43 showed bulging and frank capsular breach, respectively, were grouped according to pathological (p)EPE in radical prostatectomy specimens. Additionally, clinicopathological/immunohistochemical findings for periostin reflecting a desmoplastic stromal reaction were compared between these groups.
EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract.
Mod Pathol
March 2024
Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland.
Desmoplastic small round cell tumor (DSRCT) is a high-grade, primitive round cell sarcoma classically associated with prominent desmoplastic stroma, coexpression of keratin and desmin, and a characteristic EWSR1::WT1 gene fusion. DSRCT typically arises in the abdominopelvic cavity of young males with diffuse peritoneal spread and poor overall survival. Although originally considered to be pathognomonic for DSRCT, EWSR1::WT1 gene fusions have recently been detected in rare tumors lacking the characteristic morphologic and immunohistochemical features of DSRCT.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!