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Indian J Radiol Imaging
January 2025
Department of Medical Imaging, University of Toronto, University Medical Imaging Toronto, University Health Network, Sinai Health System, Women's College Hospital, Toronto, Canada.
The evolution of modern medicine has been significantly driven by medical and health care research, underscoring the importance of disseminating findings to advance health care. Medical literature, encompassing various publication types such as case reports, review articles, and original research, plays a crucial role in this process by facilitating the communication and discussion of new discoveries. This review article provides a comprehensive guide to understanding and navigating radiologic publications.
View Article and Find Full Text PDFA Real-World Evidence Primer for Advanced Practice Providers: Integrating P-Reality X Into Shared Decision-Making for People With HR+/HER2- Metastatic Breast Cancer.
J Adv Pract Oncol
July 2024
UCSD Comprehensive Breast Health Center, La Jolla, California.
Advanced practice providers in oncology are now likely to encounter real-world data (RWD) studies in addition to data from randomized controlled trials (RCTs) in their practice. Real-world evidence derived from RWD can provide important information about a therapeutic agent's effectiveness outside of the confines of RCTs. It is important to understand how these studies are conducted and how data from these two types of studies can be interpreted and integrated for practical clinical use and shared decision-making.
View Article and Find Full Text PDFMRPL24 drives breast cancer metastasis and stemness by targeting c-MYC, BRD4, and STAT3.
3 Biotech
February 2025
Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, 200093 China.
Unlabelled: The study aims to investigate the clinicopathological significance of MRPL24 in human cancers, with a particular focus on breast cancer (BC). Comprehensive bioinformatics analyses were conducted using data from The Cancer Genome Atlas (TCGA) and various advanced database, including cBioPortal, UALCAN, TIMER, Prognoscan, TISIDB, KM Plotter, and The Human Protein Atlas, to provide a detailed evaluation of MRPL55's role in cancer. The findings were further validated through experimental studies.
View Article and Find Full Text PDFRpoN mediates biofilm formation by directly controlling gene cluster and c-di-GMP synthetic metabolism in .
Biofilm
June 2025
State Key Laboratory of Marine Resource Utilization in the South China Sea, Hainan University, Haikou, 570228, Hainan Province, China.
is a prevalent pathogen in both humans and marine species, exhibiting high adaptability to various adverse environmental conditions. Our previous studies have shown that Δ formed three enhanced biofilm types, including spectacular surface-attached biofilm (SB), scattered pellicle biofilm (PB), and colony rugosity. However, the precise mechanism through which regulates biofilm formation has remained unclear.
View Article and Find Full Text PDFDifferential expression of in normal and tumor tissues: Implications for cancer biology and prognosis.
J Taibah Univ Med Sci
December 2024
Department of Pathology, Faculty of Medicine, Umm Al-Qura University, Makkah, KSA.
Objectives: , which is primarily recognized for determining blood types, shows variable expression patterns in different tissues and cancer types. This study investigated the relationship between gene expression and cancer, and assessed its potential impact on patient survival.
Methods: Utilizing the GEPIA database, we analyzed expression in normal and tumor tissues across various cancer types using online tools for comprehensive evaluation.
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