Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428655 | PMC |
| http://dx.doi.org/10.1016/j.nlm.2014.08.014 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.
J Prev Alzheimers Dis
January 2025
Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, BioClinicum, 171 64 Solna, Sweden; Theme Inflammation and Aging, Karolinska University Hospital, 141 86 Stockholm, Sweden.
The advancement of disease-modifying treatments (DMTs) for Alzheimer's disease (AD), along with the approval of three amyloid-targeting therapies in the US and several other countries, represents a significant development in the treatment landscape, offering new hope for addressing this once untreatable chronic progressive disease. However, significant challenges persist that could impede the successful integration of this class of drugs into clinical practice. These challenges include determining patient eligibility, appropriate use of diagnostic tools and genetic testing in patient care pathways, effective detection and monitoring of side effects, and improving the healthcare system's readiness by engaging both primary care and dementia specialists.
View Article and Find Full Text PDFNon-colorectal Cancer Screening and Vaccinations in Patients with Inflammatory Bowel Disease: Expert Review.
Clin Gastroenterol Hepatol
January 2025
Inflammatory Bowel Disease Center, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville FL. Electronic address:
Description: The aim of this American Gastroenterological Association (AGA) Clinical Practice Update (CPU) is to provide best practice advice (BPA) statements for gastroenterologists and other health care providers who provide care to patients with inflammatory bowel disease (IBD). The focus is on IBD-specific screenings (excluding colorectal cancer screening, which is discussed separately) and vaccinations. We provide guidance to ensure that patients are up to date with the disease-specific cancer screenings, vaccinations, as well as advice for mental health and general wellbeing.
View Article and Find Full Text PDFA distinct immunophenotype in children carrying the Blautia enterotype: The generation R study.
Clin Immunol
January 2025
Department of Immunology, Erasmus MC, University Medical Center, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands; Department of Immunology, Central Clinical School, Monash University and Alfred Hospital, Commercial Road 89, 3004 Melbourne, Victoria, Australia. Electronic address:
Objective: Studies in mouse models and human adults have shown that the intestinal microbiota composition can affect peripheral immune cells. We here examined whether the gut microbiota compositions affect B and T-cell subsets in children.
Methods: The intestinal microbiota was characterized from stool samples of 344 10-year-old children from the Generation R Study by performing 16S rRNA sequencing.
Signature-based intrusion detection using machine learning and deep learning approaches empowered with fuzzy clustering.
Sci Rep
January 2025
Department of Software, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam-si, 13120, Republic of Korea.
Network security is crucial in today's digital world, since there are multiple ongoing threats to sensitive data and vital infrastructure. The aim of this study to improve network security by combining methods for instruction detection from machine learning (ML) and deep learning (DL). Attackers have tried to breach security systems by accessing networks and obtaining sensitive information.
View Article and Find Full Text PDFA dual decomposition integration and error correction model for carbon price prediction.
J Environ Manage
January 2025
School of Management, Xi'an University of Architecture and Technology, Xi'an, 710055, China.
Accurately predicting carbon prices is crucial for effective government decision-making and maintenance the stable operation of carbon markets. However, the instability and nonlinearity of carbon prices, driven by the complex interaction between economic, environmental, and political factors, often result in inaccurate predictions. To confront this challenge, this paper proposed a carbon price prediction model that integrates dual decomposition integration and error correction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!