Objective: To identify factors influencing the number of fetal cells in maternal blood.
Methods: A total of 57 pregnant women at a gestational age of weeks 11-14 were included. The number of fetal cells in maternal blood was assessed in 30 ml of blood using specific markers for both enrichment and subsequent identification.
Results: Participants carrying male fetuses had a higher median number of fetal cells in maternal blood than those carrying female fetuses (5 vs. 3, p = 0.04). Certain cytokines (RANTES, IL-2 and IL-5) were significantly associated with the number of fetal cells in maternal blood.
Conclusion: The number of fetal cells in maternal blood is associated with certain cytokines and fetal gender.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154776 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106934 | PLOS |
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