The lethality of malaria in the extra-Amazonian region is more than 70 times higher than in Amazonia itself. Recently, several studies have shown that autochthonous malaria is not a rare event in the Brazilian southeastern states in the Atlantic Forest biome. Information about autochthonous malaria in the state of Rio de Janeiro (RJ) is scarce. This study aims to assess malaria cases reported to the Health Surveillance System of the State of Rio de Janeiro between 2000-2010. An average of 90 cases per year had parasitological malaria confirmation by thick smear. The number of malaria notifications due to Plasmodium falciparum increased over time. Imported cases reported during the period studied were spread among 51% of the municipalities (counties) of the state. Only 35 cases (4.3%) were autochthonous, which represents an average of 3.8 new cases per year. Eleven municipalities reported autochthonous cases; within these, six could be characterised as areas of residual or new foci of malaria from the Atlantic Forest system. The other 28 municipalities could become receptive for transmission reintroduction. Cases occurred during all periods of the year, but 62.9% of cases were in the first semester of each year. Assessing vulnerability and receptivity conditions and vector ecology is imperative to establish the real risk of malaria reintroduction in RJ.
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http://dx.doi.org/10.1590/0074-0276130558 | DOI Listing |
Small Methods
January 2025
Liquid Sunlight Alliance, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, United States.
Copper-tantalate, CuTaO (CTO), shows significant promise as an efficient photocathode for multi-carbon compounds (C) production through photoelectrochemical (PEC) CO reduction, owing to its suitable energy bands and catalytic surface. However, synthesizing CTO poses a significant challenge due to its metastable nature and thermal instability. In this study, this challenge is addressed by employing a flux-mediated synthesis technique using a sodium-based flux to create sodium-doped CTO (Na-CTO) thin films, providing enhanced nucleation and stabilization for the CTO phase.
View Article and Find Full Text PDFHypertens Res
January 2025
Department of Internal Medicine, School of Medical Sciences, State University of Campinas, Campinas, SP, Brazil.
In hemodialysis patients, blood pressure (BP) measured at the postdialysis period (POSBP) can be used to diagnose hypertension. However, the optimal time point for POSBP remains uncertain. This cross-sectional study evaluated 210 long-term dialysis patients (66.
View Article and Find Full Text PDFNat Commun
January 2025
Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, Heidelberg, Germany.
Complex experimental protocols often require multi-modal data acquisition with precisely aligned timing, as well as state- and behavior-dependent interventions. Tailored solutions are mostly restricted to individual experimental setups and lack flexibility and interoperability. We present an open-source, Linux-based integrated software solution, called 'Syntalos', for simultaneous acquisition and synchronization of data from an arbitrary number of sources, including multi-channel electrophysiological recordings and different live imaging devices, as well as closed-loop, real-time interventions with different actuators.
View Article and Find Full Text PDFArq Neuropsiquiatr
January 2025
Universidade Federal do Rio de Janeiro, Hospital Universitário Clementino Fraga Filho, Centro de Estudos em Paramiloidose Antônio Rodrigues de Mello, Rio de Janeiro RJ, Brazil.
Background: Tafamidis is a kinetic stabilizer that binds to the transthyretin (TTR) gene, inhibiting its dissociation. It is the only disease-modifying treatment for hereditary TTR amyloidosis with peripheral neuropathy (ATTRv-PN) available in the National Therapeutic Form (Formulário Terapêutico Nacional, FTN, in Portuguese) of the Brazilian Unified Health System (Sistema Único de Saúde, SUS, in Portuguese).
Objective: To assess if the efficacy and safety of tafamidis in the Brazilian real-world experience are comparable to the results of clinical trials.
Sci Total Environ
January 2025
Graduate Program in Biodiversity and Nature Conservation, Federal University of Juiz de Fora (UFJF), Minas Gerais State, Brazil; Plant Ecology Laboratory, Department of Botany, Federal University of Juiz de Fora, Juiz de Fora (UFJF), Minas Gerais State, Brazil. Electronic address:
Research about patterns of aboveground carbon stock (AGC) across different tropical forest types is central to climate change mitigation efforts. However, the aboveground carbon stock (AGC) quantification for Brazilian cloud forest ecosystems along the altitudinal gradient is still scarce. We aimed to evaluate the effects of abiotic and biotic on AGC and the AGC distribution between species and families of tree communities along an altitudinal Brazilian Atlantic cloud forest gradient of the Mantiqueira Mountain Range, Southeastern Brazil.
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