This study examines second generation (Nisei) Japanese Americans' reactions to government redress for their unjust incarceration during World War II. Structural equation modeling (SEM) was used to explore the roles of individual difference factors-Belief in a Just World (BJW), Locus of Control (LOC)-and Incarceration-Related Coping in predicting (a) reported redress-related Suffering Relief and (b) Positive Redress Impacts. Findings show that BJW was a stronger predictor of redress reactions than LOC, with higher BJW associated with more affirmative views of redress. In addition, Incarceration-Related Coping mediated a majority of the relationships between the individual difference factors and redress reactions.
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http://dx.doi.org/10.1037/a0037629 | DOI Listing |
J Appl Genet
January 2025
Department of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.
Gilles de la Tourette syndrome (GTS) and other tic disorders (TDs) have a substantial genetic component with their heritability estimated at between 60 and 80%. Here we propose an oligogenic risk score of TDs using whole-genome sequencing (WGS) data from a group of Polish GTS patients, their families, and control samples (n = 278). In this study, we first reviewed the literature to obtain a preliminary list of 84 GTS/TD candidate genes.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
July 2024
Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013.
Objectives: Genetic factors play an important role in the pathogenesis of diabetic kidney disease (DKD). Studies have shown that gene polymorphism is associated with the pathogenesis of type 2 diabetes mellitus (T2DM), but its role in DKD remains unclear. This study aims to analyze the distribution of alleles and genotypes of gene in patients with T2DM, and investigate the association between genetic polymorphism and DKD susceptibility in T2DM patients, which may provide new ideas for the pathogenesis of DKD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Ace Alzheimer Center Barcelona - International University of Catalunya (UIC), Barcelona, Spain.
Background: Alzheimer's disease (AD) is a complex disorder with a strong genetic component, yet many genetic risk factors remain unknown. Integrating genome-wide association studies (GWAS) and high-throughput proteomic platforms is a useful strategy to evaluate protein quantitative trait loci (pQTLs) and to detect candidate genes and pathways involved in AD. Due to the novelty of these techniques, the identification of reliable protein measures through a comprehensive quality control is mandatory.
View Article and Find Full Text PDFBackground: Seizures maybe associated with worse neuropathology findings in people with dementia. However, the role of seizure control and how it may impact post-mortem histopathology findings in people with dementia remains unexplored.
Method: We used the longitudinal, multicenter National Alzheimer Coordinating Center data from 9/2005 to 12/2021 to evaluate the association between seizure control and histopathological neurodegenerative changes in people with dementia.
Background: Locus coeruleus (LC) is a primary source of noradrenalin in the brain and plays a complex role in human behavior. In healthy aging and Alzheimer's disease (AD), LC cell loss has been linked to a decline in overall cognitive function. This study aimed to explore age- and AD-related differences in a proxy measure of LC activity.
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