Objectives/hypothesis: The aim of this study was to compare the volume of nasopharyngeal airways of patients with unilateral cleft lip and palate (UCLP) with a control (noncleft) group of subjects.
Study Design: Retrospective case-control study.
Methods: The sample consisted of 45 subjects, 30 with UCLP who underwent cone beam computed tomography (CBCT) exams as part of their workups for alveolar bone graft and 15 noncleft subjects seeking orthodontic care who obtained CBCT for diagnostic purposes. The three-dimensional volumes of nasal (NV) and oropharyngeal (PV) airways of these subjects were assessed separately using Mimics software by one well-calibrated evaluator. The images were rendered, and the volumes were measured in cm(3).
Results: The mean PV of the UCLP subjects was 6.7 cm(3) and the mean NV was 10.3 cm(3). The control group presented with a mean PV of 8.1 cm(3) and a mean NV of 11.6 cm(3). Student t test showed no statistically significant difference for PV (P = 0.10) or NV (P = 0.23) when comparing cleft and noncleft subjects.
Conclusion: Evaluation of the nasopharyngeal airways revealed that the NV and PV airways showed no difference between the cleft and noncleft subjects. It is interesting to postulate that the reported nasal abnormalities of the cleft patients do not produce a significant measurable effect on the overall volume, at least as shown in our study sample. In addition, the nasopharyngeal airways of patients are not larger than those of age-matched controls, at least at the ages that were sampled, after cleft palate repair.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/lary.24895 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Utilization of High-Flow Nasal Cannulas in Pediatric Critical Care: A Single-Center Experience.
Cureus
December 2024
Pediatric Intensive Care Unit, King Fahad Medical City, Riyadh, SAU.
Background: High-flow nasal cannula (HFNC) therapy has developed as a valuable tool for respiratory support in pediatric critical care. It offers an intermediate level of support between traditional low-flow oxygen and non-invasive ventilation (NIV). Studies suggest its effectiveness in improving oxygen delivery, work of breathing, and secretion clearance.
View Article and Find Full Text PDFCharacterization of Spray-Dried Powders Using a Coated Alberta Idealized Nasal Inlet.
J Aerosol Med Pulm Drug Deliv
January 2025
Department of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Dry powders offer the potential to increase stability and reduce cold-chain requirements associated with the distribution of vaccines and other thermally sensitive products. The Alberta Idealized Nasal Inlet (AINI) is a representative geometry for characterization of nasal products that may prove useful in examining intranasal delivery of powders. Spray-dried trehalose powders were loaded at 10, 20, and 40 mg doses into active single-dose devices.
View Article and Find Full Text PDFTemporal Trends in Respiratory Infection Epidemics Among Pediatric Inpatients Throughout the Course of the COVID-19 Pandemic From 2018 to 2023 in Fukushima Prefecture, Japan.
Influenza Other Respir Viruses
January 2025
Department of Pediatrics, Fukushima Medical University, Fukushima, Japan.
Background: Nonpharmaceutical interventions for coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, during the pandemic altered the epidemiology of respiratory viruses. This study aimed to determine the changes in respiratory viruses among children hospitalized from 2018 to 2023.
Methods: Nasopharyngeal specimens were collected from children aged under 15 years with fever and/or respiratory symptoms admitted to a medical institution in Fukushima Prefecture between January 2018 and December 2023.
Changes in upper airway airflow after rapid maxillary expansion considering normal craniofacial development as a factor: a retrospective study using computer fluid dynamics.
Eur J Orthod
December 2024
Department of General Surgery and Medical-Surgical Specialties, Section of Orthodontics, University of Catania, Policlinico Universitario 'Gaspare Rodolico-San Marco', Via Santa Sofia 78, 95123, Catania, Italy.
Background/objectives: Evidence suggests nasal airflow resistance reduces after rapid maxillary expansion (RME). However, the medium-term effects of RME on upper airway (UA) airflow characteristics when normal craniofacial development is considered are still unclear. This retrospective cohort study used computer fluid dynamics (CFD) to evaluate the medium-term changes in the UA airflow (pressure and velocity) after RME in two distinct age-based cohorts.
View Article and Find Full Text PDFSoft palate angle and basihyoid depth increase with tongue size and with body condition score in horses.
Equine Vet J
January 2025
University of Liverpool, Leahurst Campus, Neston, UK.
Background: Obesity has been associated with human obstructive sleep apnoea and canine brachycephalic obstructive airway syndrome. The effect of body condition score (BCS) on structures of the oropharynx, nasopharynx and upper airway of the horse has not been investigated.
Objectives: To investigate the effect of BCS on tongue measurements, soft palate angle and basihyoid depth in horses.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!