Normally present in the temporal region, the juxtaoral organ of Chievitz has considerable importance for both the surgeon and the pathologist. Although very rare, the nodular hyperplasia of the Chievitz's organ has been misinterpreted as invasive carcinoma. The pathological aspect mimics the mucoepidermoid carcinoma, squamous carcinoma, basal cell carcinoma with sebaceous differentiation or tumor of the skin appendages. We present the case of a 71-year-old patient admitted with temporal tumor. The initial pathological diagnosis was mixed squamous basal cell carcinoma. The subsequent evaluation of sections and immunohistochemistry allowed us to demonstrate a benign tumor of the Chievitz's organ. In this case, therapy and prognosis are strongly related to the correct diagnosis and avoid an over treatment of a benign tumor.
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Ann Surg
January 2025
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Objective: To investigate the clinicopathological features and long-term outcomes of cystic and solid pancreatic neuroendocrine tumors (PanNETs).
Summary Background Data: PanNETs uncommonly present as cystic lesions. Whether cystic PanNETs represent a distinct clinical entity compared to solid PanNETs is controversial.
Arterioscler Thromb Vasc Biol
January 2025
Cardiovascular Research Center, New York University Langone Health, New York University Grossman School of Medicine. (A.A.C.N., J.M.D., K.J.M.).
The field of cardio-oncology has traditionally focused on the impact of cancer and its therapies on cardiovascular health. Mounting clinical and preclinical evidence, however, indicates that the reverse may also be true: cardiovascular disease can itself influence tumor growth and metastasis. Numerous epidemiological studies have reported that individuals with prevalent cardiovascular disease have an increased incidence of cancer.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
January 2025
Department of Orthopedics and Traumatology, Ondokuz Mayıs University, Samsun, Turkey.
Purpose Of The Study: Open (incisional) biopsies have long been accepted as the gold standard in diagnosing bone and soft tissue tumors. However, the main disadvantage of this method is that it can lead to increased contamination, hematoma, infection, and pathological fracture. Compared to open biopsies, percutaneous core needle biopsies are less invasive, do not require hospitalization, have low costs and low complication rates, and there is no need for wound healing in cases that require radiotherapy.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
January 2025
University of Pisa, Department of Orthopedic and Trauma Surgery, Pisa, Italy.
Purpose Of The Study: Hand enchondromas are benign cartilage bone tumors. Curettage represents the actual gold standard for hand enchondromas. Little has been written about the effectiveness of curettage on hand functionality.
View Article and Find Full Text PDFFASEB J
January 2025
Department of Hematology, Nephrology, and Rheumatology, Graduate School of Medicine, Akita University, Akita, Japan.
Various tubular diseases in patients with multiple myeloma (MM) are caused by monoclonal immunoglobulin light chains (LCs). However, the physicochemical characteristics of the disease-causing LCs contributing to the onset of MM-associated tubular diseases remain unclear. We herein report a rare case of MM-associated combined tubulopathies: non-crystalline light chain proximal tubulopathy (LCPT) and crystalline light chain cast nephropathy (LCCN).
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