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Cryoneurolysis and Quadriplegia: A Case Report on Pain and Severe Spasticity Management.
Arch Rehabil Res Clin Transl
December 2024
Vancouver Island Health Authority, Victoria, BC, Canada.
Spasticity, a common symptom after spinal cord injury, often leads to pain, muscle contracture, and compromised daily activities. Cryoneurolysis, a minimally invasive, drug-free procedure for the treatment of pain, is now gaining recognition for treating spasticity. It involves using an ultrasound-guided probe to freeze and destroy overactive target nerves.
View Article and Find Full Text PDFBackground: With the clinical integration of sugammadex, a selective relaxant-binding agent, the approach to reversing neuromuscular blockade is revolutionized. Despite its efficacy, sugammadex's adverse reactions range from mild symptoms to severe cases, including anaphylaxis and coagulopathy. Assessing the nature of these reactions using the Food and Drug Administration's Adverse Event Reporting System (FAERS) database is vital for safe anesthetic practice.
View Article and Find Full Text PDFComplications of intravascular brachytherapy.
Brachytherapy
January 2025
Department of Radiation Oncology, University of Washington, Seattle, WA.
Introduction: There is some evidence of a dose-response relationship for intravascular brachytherapy (IVBT) of native vessel or first-time in-stent restenosis (ISR). It has also been shown that in-field failure predominates following intravascular brachytherapy-treated lesions. Accordingly, it may be advantageous to increase the radiation dose(s) currently used.
View Article and Find Full Text PDFAblation options for sub-epicardially located ventricular substrates responsible for ventricular tachycardia: where is it all headed?
Curr Opin Cardiol
January 2025
Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Article Synopsis
- Patients with nonischemic and ischemic cardiomyopathy often experience re-entrant tachycardias related to scar tissue, making effective treatment challenging despite technological advances in mapping and ablation.
- Currently, percutaneous epicardial ablation is the preferred method after endocardial ablation fails, but high recurrence rates are a concern, with some energy sources like pulsed-field having limitations.
- New cryoablation technology using liquid helium shows promise for better outcomes in treating ventricular arrhythmias associated with subepicardial targets in NICM and ICM patients.
Novel Index Combining Pan-Immune-Inflammatory Index and Hemoglobin Levels (PIV/Hb) Predicts Trismus Rates Efficiently after Chemoradiotherapy in Locally Advanced Nasopharyngeal Cancer.
Int J Surg Oncol
October 2024
Department of Radiation Oncology School of Medicine Koc University, Istanbul, Türkiye.
Article Synopsis
- The study investigates a new index combining immune-inflammation markers and hemoglobin levels (PIV/Hb) to predict radiation-induced trismus (RIT) in patients with locally advanced nasopharyngeal cancer undergoing chemoradiotherapy.
- Data from 228 patients were analyzed, measuring mouth openings to confirm RIT and calculating PIV/Hb from blood tests taken on the first day of treatment.
- Results show that higher PIV/Hb levels (specifically >68 g/dL) significantly correlate with increased rates of RIT, indicating that this index could be a useful predictor for clinicians.
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