Background And Objectives: Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.
Methods: Totally 120 patients with laryngeal cancer were observed (T2-3 N0-1 M0 ). We have developed a method of laryngeal reconstruction using TiNi-based endografts. All endografts show the superelastic behavior recovering the shape. All patients have undergone different types of sparing surgeries with simultaneous replacement with endografts.
Results: Voice function was completely saved in 112 cases and partially in 8 ones. Respiratory function was fully restored in 106 patients. The protective function of the larynx was achieved in 116 patients.
Conclusion: The technique allowed to achieve well oncological (the 5-year and overall recurrence-free survival rates of all 120 patients were 83% and 76%, respectively) and functional (larynx function was saved in 93% of cases) outcomes after extensive and subtotal resections in patients with locally distributed larynx cancer.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/jso.23779 | DOI Listing |
J Funct Biomater
June 2019
Department of Physical Metallurgy and Materials Technology, Brandenburg University of Technology, 03044 Cottbus, Germany.
Repairs of orbital post-traumatic and extensive malignant defects remain a major surgical challenge, in view of follow-up outcomes. Incorrect surgical management of injured facial structures results in cosmetic, ophthalmic, and social aftereffects. A custom-made knitted TiNi-based mesh (KTNM) endograft was employed to overcome post-surgical complications and post-resected lesions of the orbital area.
View Article and Find Full Text PDFCase Rep Oncol
November 2016
Tomsk State University, Tomsk, Russian Federation.
Published reports on salvage treatment for trachea reconstruction after total thyroidectomy or partial tracheotomy are available, some of them using structures of the trachea itself, auricular cartilage, a musculocutaneous flap, or other methods. In our report, we emphasize the importance of a search for a new material and approach for sparing surgery. The purpose of this article is to describe a case of a successful sparing surgery in a patient with advanced thyroid papillary carcinoma invading the trachea.
View Article and Find Full Text PDFJ Surg Oncol
February 2015
Tomsk Cancer Research Institute, Russian Academy of Medical Science, Tomsk, Russia.
Background And Objectives: Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.
Methods: Totally 120 patients with laryngeal cancer were observed (T2-3 N0-1 M0 ). We have developed a method of laryngeal reconstruction using TiNi-based endografts.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!