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Objective: This study evaluated the in situ rehardening effect of a commercial chewing gum containing casein phosphopeptide - amorphous calcium phosphate (CPP-ACP) on initial erosion lesions.
Methods: Seventy-two human enamel blocks, after selection (initial surface hardness - SHi) and in vitro short-term acidic exposure (cola drink for 3 min - SHd) were randomly assigned to three groups. The factors under study were treatment (3 levels: GI chewing gum with CPP-ACP, GII chewing gum without CPP-ACP and GIII control group without gum) and intraoral period (2 levels: 2 and 24h). Twelve volunteers wore intraoral palatal devices for 24h in 3 crossover phases. On each phase, after 2h the surface hardness was assessed (SHf1) and the blocks were reinserted and the devices were used for additional 22 h (SHf2). In phases of GI and GII volunteers chewed the respective gum during 30 min, for 4 times with an interval of 4h. Percentage of surface hardness recovery (%SHR) was calculated after 2 and 24 h. The data were analysed by repeated measures ANOVA and Tukey's test.
Results: Chewing gum with CPP-ACP (2h=50.0%<24h=95.9%) showed higher hardness recovery than chewing gum without CPP-ACP (2h=30.0%<24 h=71.1%) and control (2 h=15.7%<24 h=40.9%) (p<0.05).
Conclusions: The results suggest that saliva increased hardness of softened enamel after the use of conventional chewing gum (GII) and this effect was enhanced by the prolonged intraoral period (24 h) and by the use of CPP-ACP chewing gum (GI).
Clinical Significance: Since chewing gum is an alternative to enhance salivary defenses after erosive challenges, CPP-ACP chewing gum might be a supplementary strategy to potentiate the mineral precipitation of initial erosion lesions.
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http://dx.doi.org/10.1016/j.jdent.2014.08.008 | DOI Listing |
Front Syst Neurosci
November 2024
Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Introduction: Chewing has been reported to enhance cognitive function through the increase in cerebral blood flow. However, the mechanisms linking cerebral blood flow increase to metabolic changes in the brain affecting cognition remain unclear. We hypothesized that glutathione (GSH) plays a pivotal role in these mechanisms.
View Article and Find Full Text PDFClin Kidney J
December 2024
School of Nursing and Midwifery, University of Newcastle, Newcastle, NSW, Australia.
Background: Xerostomia is a distressing symptom experienced by patients undergoing dialysis. We sought to compare and rank the efficacy of different non-pharmacological interventions on xerostomia and salivary flow rate among dialysis patients.
Methods: A systematic search was conducted in six English-language databases: PubMed, CINAHL, Scopus, Web of Science, Embase and Cochrane Central Register of Controlled Trials, in April 2023.
Mol Ther
December 2024
Department of Basic & Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lack of Herpes Simplex Virus (HSV) vaccine, low vaccination rates of Influenza viruses, waning immunity and viral transmission after vaccination underscore the need to reduce viral loads at their transmission sites. Oral virus transmission is several orders of magnitude higher than nasal transmission. Therefore, in this study, we evaluated neutralization of viruses using a natural viral trap protein (FRIL) formulated in clinical-grade chewing gum.
View Article and Find Full Text PDFJ Int Soc Sports Nutr
December 2024
Department of Sport Sciences, Faculty of Education and Psychology, Shiraz University, Shiraz, Iran.
Background: Athletes require proper nutrition to enhance training and performance. Studies indicate that alternative sources of caffeine, such as caffeinated chewing gum, mouth rinses, energy gels, and coffee can improve performance. Therefore, this study investigated the impact of consuming caffeinated gum (CG) and repeated coffee mouth rinsing (CMR) on professional male table tennis players' aerobic capacity and explosive power.
View Article and Find Full Text PDFWaste Manag
December 2024
Legambiente Onlus, Via Salaria, 403 - 00199 Rome, Italy.
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