AI Article Synopsis
- The study aimed to assess how transepithelial corneal collagen cross-linking (TE CXL) affects the mechanical properties of the cornea in patients with progressive keratoconus.
- It was conducted at the Second University of Naples, involving 36 patients who were monitored for six months using various eye measurement techniques.
- Results showed a significant improvement in best corrected visual acuity after treatment, while other corneal measurements remained stable, indicating that TE CXL helps stabilize keratoconus without compromising corneal elasticity.
Article Abstract
Purpose: To evaluate keratoconus biomechanical changes after transepithelial corneal collagen cross linking (TE CXL) using riboflavin and ultraviolet A (UVA).
Setting: Second University of Naples, Naples, Italy.
Design: Prospective non comparative case series study.
Methods: Patients with progressive keratoconus were examined, before and during a 6 months follow up after TE CXL, with a Pentacam, an Ocular Response Analyzer and an IOLMaster. Best corrected visual acuity (BCVA), refraction, corneal thinnest point (CTP), keratometry readings at the keratoconus apex (Kmax), axial eye length (AL), corneal volume (CV) anterior chamber volume (ACV), anterior chamber depth (ACD), corneal hysteresis (CH) and corneal resistance factor (CRF) were evaluated.
Results: Thirty-six eyes of 36 patients with progressive keratoconus were analyzed. Six months after treatment there was a significant improvement in BCVA (p<0.01), no significant changes in refraction (p=0.57), CTP (p=0.07), Kmax (p=0.88), AL (p=0.07), CV (p=0.38), ACV (p=0.07), ACD (p=0.7), CH (p=0.1) and CRF (p=0.3).
Conclusions: According to our results TE CXL stabilizes most of the patients with progressive keratoconus, without affecting in negative way the corneal elasticity.
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| http://dx.doi.org/10.1016/j.clae.2014.07.007 | DOI Listing |
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