The viability of Drosophila melanogaster was measured in three conditions: (1) of eggs from parents living at different gravity levels (1-5 g), developed at 1 g; (2) of eggs from parents living at 1 g, developed at different gravity levels, and (3) of eggs developed at the gravity at which their parents were kept. Hypergravity (HG) decreased viability to a low extent in all three cases (75% of emergence in the worst case). The effects of keeping parent flies in HG and of growing their offspring in HG were not cumulative. The results are discussed in relation with Pearl's rate of living theory.
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http://dx.doi.org/10.1159/000213034 | DOI Listing |
Sci Rep
January 2025
Advanced Glass and Glass Ceramic Research Laboratory, Department of Physics, University of Lucknow, Lucknow, 226007, India.
Recently, 3-D porous architecture of the composites play a key role in cell proliferation, bone regeneration, and anticancer activities. The osteoinductive and osteoconductive properties of β-TCP allow for the complete repair of numerous bone defects. Herein, β-TCP was synthesized by wet chemical precipitation route, and their 3-D porous composites with HBO and Cu nanoparticles were prepared by the solid-state reaction method with improved mechanical and biological performances.
View Article and Find Full Text PDFExpert Opin Drug Discov
January 2025
Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Introduction: Kabuki Syndrome (KS) is a rare genetic disorder characterized by distinctive facial features, intellectual disability, and multiple congenital anomalies. It is caused by pathogenic variants in the and genes. Despite its significant disease burden, there are currently no approved therapies for KS, highlighting the need for advanced research and therapeutic development.
View Article and Find Full Text PDFPharm Biol
December 2025
The Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, China.
Context: The decline in ovarian reserve is a major concern in female reproductive health, often associated with oxidative stress and mitochondrial dysfunction. Although ginsenoside Rg1 is known to modulate mitophagy, its effectiveness in mitigating ovarian reserve decline remains unclear.
Objective: To investigate the role of ginsenoside Rg1 in promoting mitophagy to preserve ovarian reserve.
Life (Basel)
January 2025
Monell Chemical Senses Center, Philadelphia, PA 19104, USA.
Chemosensation and mechanosensation are vital to insects' survival and behavior, shaping critical physiological processes such as feeding, metabolism, mating, and reproduction. During feeding, insects rely on diverse chemosensory and mechanosensory receptors to distinguish between nutritious and harmful substances, enabling them to select suitable food sources while avoiding toxins. These receptors are distributed across various body parts, allowing insects to detect environmental cues about food quality and adjust their behaviors accordingly.
View Article and Find Full Text PDFInsects
January 2025
Centre for Mind/Brain Sciences (CIMeC), University of Trento, 38068 Rovereto, Italy.
severely damages the production of berry and stone fruits in large parts of the world. Unlike , which reproduces on overripe and fermenting fruits on the ground, prefers to lay its eggs in ripening fruits still on the plants. Flies locate fruit hosts by their odorant volatiles, which are detected and encoded by a highly specialised olfactory system before being translated into behaviour.
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