AI Article Synopsis
- Endocrine changes such as adrenal insufficiency, growth and puberty disorders, thyroid dysfunction, metabolic issues, and osteopenia are common in pediatric HIV patients.
- These changes result from various factors, including the direct impact of the HIV virus and the effects of antiretroviral treatments.
- Such endocrine alterations are particularly concerning during childhood due to the vital developmental processes happening during this stage and the possibility of long-term exposure to HIV and medications.
Article Abstract
Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.
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| http://dx.doi.org/10.1016/j.ecl.2014.06.001 | DOI Listing |
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