AI Article Synopsis
- Cases of invasive mycosis from Blastobotrys serpentis and B. proliferans were reported in a preterm patient and a patient with rhabdomyosarcoma.
- These species showed high minimum inhibitory concentrations (MICs) for fluconazole and echinocandin, indicating resistance to these treatments.
- B. serpentis also had elevated MICs for amphotericin B, creating further difficulties in treating the infections.
Article Abstract
Cases of invasive mycosis due to Blastobotrys serpentis and B. proliferans identified by sequencing in a preterm patient and a rhabdomyosarcoma patient, respectively, are reported. Both species revealed elevated fluconazole and echinocandin MICs by the CLSI broth microdilution method. Additionally, B. serpentis exhibited high amphotericin B MICs, thus posing serious therapeutic challenges.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313262 | PMC |
| http://dx.doi.org/10.1128/JCM.01977-14 | DOI Listing |
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