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Detection of male genital schistosomiasis (MGS) associated with human, zoonotic and hybrid schistosomes in Southern Malawi.
BMC Infect Dis
August 2024
Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, CTID Building, Pembroke Place, Liverpool, Merseyside, L3 5QA, UK.
Article Synopsis
- * Researchers collected demographic and health data, along with urine and semen samples from 22 men, finding high rates of schistosome infection and co-infection with HPV and other STIs.
- * The study highlights the complex interactions between zoonotic and hybrid schistosomes in causing MGS, illustrating significant challenges for diagnosis and treatment in low-resource areas.
Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protocol.
BMJ Open
May 2023
Research Department of Infection, Division of Infection and Immunity, UCL, London, UK.
Introduction: Vaccination is a potentially critical component of efforts to arrest development and dissemination of antimicrobial resistance (AMR), though little is known about vaccination impact within low-income and middle-income countries. This study will evaluate the impact of vaccination on reducing carriage prevalence of resistant and extended spectrum beta-lactamase-producing and species. We will leverage two large ongoing cluster-randomised vaccine evaluations in Malawi assessing; first, adding a booster dose to the 13-valent pneumococcal conjugate vaccine (PCV13) schedule, and second, introduction of the RTS,S/AS01 malaria vaccine.
View Article and Find Full Text PDFIntroduction: Although knowledge of HIV positivity is a necessary step towards engagement in HIV care, more than one quarter of HIV-positive Malawians remain unaware of their HIV status. Testing the sexual partners, guardians and children of HIV-positive persons (index case finding or ICF) is a promising way of identifying HIV-positive persons unaware of their HIV status. ICF can be passive where the HIV-positive individual (index) invites a partner (or contact) for HIV testing or active where a health provider assists the index with partner notification and offers HIV testing to the partner.
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