Statement Of Problem: A silicone prosthesis used to rehabilitate defects caused by cancer does not usually protect the underlying skin from ultraviolet light. Additives to the maxillofacial material may add ultraviolet protection.
Purpose: The purpose of this study was to evaluate the degree of ultraviolet protection after incorporating varying concentrations of nano-oxides in Cosmesil M511 medical grade silicone elastomer.
Material And Methods: Nanosized oxides of Zn and Ti were added in various concentrations (0.5%, 1.0%, 1.5%, 2.0%, and 2.5% by weight) to a silicone elastomer. Cosmesil M511 silicone without nano-oxides served as the control group for 11 experimental groups. All specimens were subjected to ultraviolet radiation with ultraviolet A (>315-400 nm) and ultraviolet B (>280-315 nm), and the percentage transmission was measured with an ultraviolet spectrophotometer. The ultraviolet protection factor was calculated. The Mann-Whitney U test was used to evaluate which of the groups differed significantly (α=.05). The Wilcoxon signed rank test was used to test the difference in values obtained for both ultraviolet ranges.
Results: Spectrophotometric analysis indicated that the percentage-of-transmission values decreased for both the nano-oxide groups for the ultraviolet A and B ranges (P<.05) compared with the control group. The ultraviolet protection factor values increased considerably as the percentage concentration of nano-oxides was increased for both ultraviolet ranges (P<.05).
Conclusions: Compared with Ti nano-oxides (2% to 2.5%), Zn nano-oxides in lesser concentrations provided more significant and consistent ultraviolet protection in Cosmesil M511 elastomer.
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| http://dx.doi.org/10.1016/j.prosdent.2014.07.001 | DOI Listing |
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