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Enoxaparin-Induced Liver Injury.

Case Rep Gastroenterol

June 2020

Department of Gastroenterology, Bronx Care Health System, Bronx, New York, USA.

Enoxaparin, a form of low-molecular-weight heparin, can cause a rare, underreported, and often reversible form of hepatocellular injury. This report describes a case of enoxaparin-induced hepatotoxicity in a 61-year-old male diagnosed with pulmonary embolism. Elevations of liver enzymes were noted within 1 week of starting the drug, followed by a dramatic improvement upon its discontinuation, with subsequent normalization in the following days.

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Enoxaparin-induced hepatotoxicity: an under-recognised complication of enoxaparin therapy.

BMJ Case Rep

September 2016

Department of Medicine, Warren Alpert School of Medicine, Brown University, The Miriam Hospital, Providence, Rhode Island, USA.

Low-molecular-weight heparins including enoxaparin are commonly used for anticoagulation as prophylaxis and treatment for deep vein thrombosis (DVT). Prescribers of enoxaparin monitor for common side effects, such as bleeding and thrombocytopenia, but hepatotoxicity, a less common and under-reported adverse effect, may be overlooked. This report describes a case of enoxaparin-induced hepatotoxicity in a 57-year-old man who was started on the drug for a DVT.

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Probable enoxaparin-induced hepatotoxicity.

Am J Health Syst Pharm

April 2009

Evidence-Based Practice Center, Hartford Hospital, Hartford, CT, USA.

Purpose: A case of probable enoxaparin-induced hepatotoxicity is described.

Summary: A 29-year-old woman sought treatment from a pulmonologist for a dry, hacking, constant cough not relieved by fast-acting inhalers or narcotic cough medications that had lasted for three weeks. Her primary care physician had earlier made a preliminary diagnosis of pertussis and prescribed a short course of azithromycin and corticosteroids, which did not help relieve the symptoms.

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