Purpose: The goal of this study is to increase patient safety in parallel transmission (pTx) MRI systems. A major concern in these systems is radiofrequency-induced tissue heating, which can be avoided by specific absorption rate (SAR) prediction and SAR monitoring before and during the scan.
Methods: In this novel comprehensive safety concept, the SAR is predicted prior to the scan based on precalculated fields obtained from electromagnetic simulations on different body models. The radiofrequency fields and the global and local SAR are supervised in real time during the scan. This concept is integrated into a 3 T pTx MR scanner and validated experimentally.
Results: Phantom and in vivo experiments successfully validated the basic feasibility of the real-time SAR supervision concept. Supervising the SAR minimizes SAR overestimation. Monitoring the radiofrequency fields allows the detection of unsafe radiofrequency situations for the patient, which a SAR supervision system alone cannot detect.
Conclusion: This study demonstrates safe scanning in a pTx system. This new safety concept is also applicable for field strengths above 3 T and represents an important step toward safe operation of pTx systems.
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http://dx.doi.org/10.1002/mrm.25425 | DOI Listing |
Disabil Rehabil
January 2025
Department of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand.
Purpose: Medication often falls short in controlling tremors in Parkinson's disease. While physical activities suggest potential benefits, current exercise regimes have limitations. This paper explores the concept of deliberate shaking as an intervention to aid exercise uptake and potentially leverage synergies between medication and physical activity.
View Article and Find Full Text PDFTraffic Inj Prev
January 2025
Waymo LLC, Mountain View, California, USA.
Objective: The public, regulators, and domain experts alike seek to understand the effect of deployed SAE level 4 automated driving system (ADS) technologies on safety. The recent expansion of ADS technology deployments is paving the way for early stage safety impact evaluations, whereby the observational data from both an ADS and a representative benchmark fleet are compared to quantify safety performance.
Methods: In January 2024; a working group of experts across academia, insurance, and industry came together in Washington, DC to discuss the current and future challenges in performing such evaluations.
J Adv Nurs
January 2025
School of Nursing and Midwifery, Centre for Quality and Patient Safety Research, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia.
Aim(s): To identify and synthesise available evidence about regular medication management processes, from preadmission to discharge from hospital, in patients with cancer undergoing surgery.
Design: Mixed-methods systematic review.
Methods: Studies published from inception of each database until February 2023 were screened, utilising four main search concepts.
Front Physiol
January 2025
Environmental Physiology Group, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Background And Aim: Hyperventilation before breath-hold diving (freediving) is widely accepted as a risk factor for hypoxic syncope or blackout (BO), but there is no practical way to address it before dives. This study explores the feasibility of using a force sensor to predict end-tidal carbon dioxide ( CO) to assess hyperventilation in freedivers.
Methods And Results: Twenty-one freedivers volunteered to participate during two national competitions.
Drugs R D
January 2025
Department of Pediatric Intensive Care Unit, Shandong, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Road, Ji'nan, Shandong, China.
Background And Objective: Alglucosidase alfa for injection is used as an enzyme replacement therapy for the treatment of Pompe disease. The safety profile of alglucosidase alfa-associated adverse events requires a comprehensive evaluation. In this study, we aimed to identify drug safety alert signals and investigate the real-world safety of alglucosidase alfa to guide clinical decision making and optimize the risk-benefit balance.
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