Background: Adolescence is a peak time for the onset of depression, but little is known about what adolescents can do to reduce their own level of risk. To fill this gap, a review was carried out to identify risk and protective factors for depression during adolescence that are modifiable by the young person.
Methods: Employing the PRISMA method, we conducted a systematic review and meta-analysis of longitudinal studies to identify risk and protective factors during the adolescent period (aged 12-18 years) that are potentially modifiable by the young person without professional intervention or assistance. Stouffer׳s method of combining p values was used to determine whether associations between variables were reliable, and meta-analyses were conducted to estimate the mean effect sizes of associations.
Results: We identified 113 publications which met the inclusion criteria. Putative risk factors implicated in the development of depression for which there is a sound evidence base, and which are potentially modifiable during adolescence without professional intervention, are: substance use (alcohol, tobacco, cannabis, other illicit drugs, and polydrug use); dieting; negative coping strategies; and weight. Modifiable protective factors with a sound evidence base are healthy diet and sleep.
Limitations: Limitations include not systematically reviewing moderators and mediators, the lack of generalisability across cultures or to younger children or young adults, and the inability to conduct a meta-analysis on all included studies.
Conclusions: Findings from this review suggest that future health education campaigns or self-help prevention interventions targeting adolescent depression should aim to reduce substance use (alcohol, tobacco, cannabis, other illicit drugs, and polydrug use); dieting; and negative coping strategies; and promote healthy weight; diet; and sleep patterns.
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http://dx.doi.org/10.1016/j.jad.2014.08.006 | DOI Listing |
Mol Biol (Mosk)
December 2024
Pirogov All-Russia National Research Medical University, Moscow, 117997 Russia.
Obesity is associated with changes in the gut microbiota, as well as with increased permeability of the intestinal wall. In 130 non-obese volunteers, 57 patients with metabolically healthy obesity (MHO), and 76 patients with metabolically unhealthy obesity (MUHO), bacterial DNA was isolated from stool samples, and the 16S rRNA gene was sequenced. The metabolic profile of the microbiota predicted by PICRUSt2 (https://huttenhower.
View Article and Find Full Text PDFIn recent decades, biodiversity loss has greatly impacted planetary and human health. Children are at additional risk of adverse effects due to unique biological, developmental, and behavioral factors, as well as their longer exposure to an altered planet as a function of their young age. These effects are heightened for children living in vulnerable socioeconomic conditions.
View Article and Find Full Text PDFCardiovasc Diabetol
December 2024
Saw Swee Hock School of Public Heath, National University of Singapore, Singapore, 117549, Republic of Singapore.
Background: Data on the relationship between potassium intake and major cardiovascular events (MACE) in patients with diabetes are scarce. We aim to study the association between estimated potassium intake and risk of MACE in individuals with type 2 diabetes.
Methods: The discovery cohort consisted of 1572 participants with type 2 diabetes from a secondary hospital.
BMC Womens Health
December 2024
Nutrilite Health Institute, 720 Cailun Road, 201203, Shanghai, China.
Background: Primary ovarian insufficiency (POI) is a critical cause of infertility and is increasingly recognized as a complex metabolic disorder. Dietary factors may influence the risk of POI, but causal relationships remain unclear.
Methods: We conducted an MR study using genetic instrumental variables for 83 dietary preferences from the UK Biobank, with the Inverse Variance Weighted method as the primary analysis.
BMC Public Health
December 2024
Department of Life Sciences, School of Sciences, European University Cyprus, 6 Diogenes Str. Engomi, 2404, P.O. Box: 22006, Nicosia, 1516, Cyprus.
Background: Malnutrition, depression, and cognitive decline are significant concerns among the elderly population, yet the relationship between these factors remains underexplored, particularly in Cyprus. This study aimed to assess the prevalence of malnutrition, depression, and cognitive decline in free-living elderly people in Cyprus and to explore the associations between these conditions and various anthropometric, social, and dietary factors.
Methods: A cross-sectional study was conducted with 248 participants aged ≥ 60 years, using convenience sampling.
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