Antimicrobial glycoalkaloids from the tubers of Stephania succifera.

Arch Pharm Res

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.

Published: April 2017

AI Article Synopsis

  • Three new glycoalkaloids were discovered in the tubers of Stephania succifera: N-formyl-asimilobine-2-O-β-D-glucoside (1), (-)-1-O-β-D-glucoside-8-oxotetrahydropalmatine (2), and 1-N-monomethylcarbamate-argentinine-3-O-β-D-glucoside (3).
  • Their structures were confirmed through spectroscopic analysis.
  • The antimicrobial activities of all three glycoalkaloids were investigated and reported.

Article Abstract

Three new glycoalkaloids, N-formyl-asimilobine-2-O-β-D-glucoside (1), (-)-1-O-β-D-glucoside-8-oxotetrahydropalmatine (2), and 1-N-monomethylcarbamate-argentinine-3-O-β-D-glucoside (3) were isolated from tubers of Stephania succifera. The structures were established based on spectroscopic analysis, and the antimicrobial activities of the three glycoalkaloids are reported.

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http://dx.doi.org/10.1007/s12272-014-0467-5DOI Listing

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