Introduction: This article introduces the modification of 4-miniplate-assisted orthopedic protocol for class III correction. Instead of bilateral mandibular miniplates between lateral incisors and canine, the single modified Y-type C-tube with extension arms can replace 2 miniplates for temporary skeletal anchorage with advantages.
Methods: Y-type C-tube was modified to have 2 extension arms for the application of class III elastics to replace 2 separate miniplates on either side of the mandible. A patient who declined a facemask therapy was selected to receive the modified protocol using only 3 C-tubes for bone-anchored maxillary orthopedic traction. The modified Y-type C-tube was inserted at the mandibular symphysis, and the bifurcation of the extension arms exited the tissue near the mucogingival junction.
Results: The modified Y-type C-tube was placed on the mandibular symphysis, and this provided 3 advantages compared with conventional miniplates: (1) 1 C-tube placement warrants less surgical sites than 2-miniplate installation, (2) placing the C-tube in between mandibular incisors prevents damage to developing or erupting permanent canines and allows early treatment start, and (3) the characteristic bendability of extension arms permits easy alteration on position and results in the vertical and sagittal vector controls of class III elastics. When the treatment is finished, it can be also simply removed like any other C-tubes with simple detachment of extension arms.
Conclusions: The modification of 4-miniplate-assisted orthopedic protocol for class III correction provides easier surgical placement of miniplates by minimizing complications, early initiation of treatment, and more vector control with bendable extension arms of the modified Y-type C-tube.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/SCS.0000000000000953 | DOI Listing |
Cureus
December 2024
Pulmonology, King Abdulaziz Medical City, Jeddah, SAU.
A 52-year-old female patient with a history of atrial septal defect repair presented with progressive dyspnea and echocardiographic findings suggestive of pulmonary hypertension (PH). Incidentally, a lung mass was discovered on computed tomography (CT). Initial evaluation revealed World Health Organization functional class III symptoms and significant weight loss.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, China.
Receptor activator of nuclear factor kappa-B ligand (RANKL) initiates a complex signaling cascade that is crucial for inducing osteoclast differentiation and activation. RANKL-induced signaling has been analyzed in detail, and the involvement of TNF receptor-associated factor 6 (TRAF6), calmodulin-dependent protein kinase (CaMK), NF-κB, mitogen-activated protein kinase (MAPK), activator protein-1 (AP-1), and molecules that contain an immunoreceptor tyrosine-based activation motif (ITAM) has been reported. However, the precise molecular steps that regulate RANKL signaling remain largely unknown.
View Article and Find Full Text PDFBone Marrow Transplant
January 2025
Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.
Belumosudil is a first in class ROCK2-inhibitor approved by the FDA for the 3rd line treatment of chronic graft-versus-host disease (cGvHD). In this retrospective real-world analysis, we report safety and efficacy data of belumosudil treatment from 5 German/Swiss transplant centers. A total of 33 adult patients (median age 59 years) with moderate (n = 2) or severe (n = 31) cGvHD were treated on individual request due to lack of EMA approval.
View Article and Find Full Text PDFObjective: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for the care of patients with vascular trauma with the aim of assisting physicians in selecting the optimal management strategy.
Methods: The guidelines are based on scientific evidence completed with expert opinion. By summarising and evaluating the best available evidence, recommendations for the evaluation and treatment of patients have been formulated.
Eur J Heart Fail
January 2025
Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Aims: Hyperglycaemic conditions increase cardiac stress, a common phenomenon associated with inflammation, aging, and metabolic imbalance. Sodium-glucose cotransporter 2 inhibitors, a class of anti-diabetic drugs, showed to improve cardiovascular functions although their mechanism of action has not yet been fully established. This study investigated the effects of empagliflozin on cardiomyocytes following high glucose exposure, specifically focusing on inflammatory and metabolic responses.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!