Salvia tomentosa essential oils from Greece were studied for the first time here. The oils from five populations growing in Mediterranean pine forests on the island of Thassos (northern Aegean Sea) and from 14 populations situated in deciduous forests in Thrace (northeastern Greek mainland) were investigated. Their essential-oil contents ranged from 1.1 to 3.3% (v/w, based on the dry weight of the plant material). The populations from Thassos had high contents of α-pinene (18.0 ± 2.9%), 1,8-cineole (14.7 ± 3.0%), cis-thujone (14.0 ± 6.9%), and borneol (12.8 ± 2.2%) and smaller amounts of camphene, camphor, and β-pinene, whereas the populations from Thrace showed high α-pinene (16.7 ± 4.0%), β-pinene (22.8 ± 4.5%), camphor (18.3 ± 4.3%), and camphene (10.3 ± 2.4%) contents, much lower 1,8-cineole and borneol amounts, while cis-thujone was completely lacking. The comparison of the present results with published data showed that oils having cis-thujone as one of the main compounds were reported for the first time here. Multivariate statistical analyses indicate that the observed essential-oil variation was related to geographical and environmental factors.
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http://dx.doi.org/10.1002/cbdv.201300408 | DOI Listing |
Bioorg Chem
October 2024
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address:
Four new diterpenoid tropolones, salvirrddones A-D (1-4), and four new icetexanes, salvirrddices A-D (9-12), along with thirteen new 11,12-seco-norabietane diterpenoids, salvirrddnor A-M (14-24, 31, 32) and sixteen known compounds (5-8, 13, 25-30, 33-37), were isolated from the roots and rhizomes of Salvia castanea Diels f. tomentosa Stib. Their structures were elucidated by comprehensive spectroscopic analyses, quantum chemical calculations, and X-ray crystallography.
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June 2024
Binzhou Medical University, Shandong, China.
Pulmonary fibrosis is a progressive, irreversible, chronic interstitial lung disease associated with high morbidity and mortality rates. Current clinical drugs, while effective, do not reverse or cure pulmonary fibrosis and have major side effects, there are urgent needs to develop new anti-pulmonary fibrosis medicine, and corresponding industrially scalable process as well. Diels f.
View Article and Find Full Text PDFMolecules
January 2024
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Methanolic-aqueous extracts of Miller roots, aerial parts, and inflorescences were examined for their content of polyphenolic derivatives and the antimicrobial and cytotoxic effect. In the polyphenolic-rich profile, rosmarinic, salvianolic, and lithospermic acids along with various derivatives were predominant. A total of twenty phenolic compounds were identified using the UPLC/DAD/qTOF-MS technique.
View Article and Find Full Text PDFPhytochemistry
February 2024
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China. Electronic address:
Six undescribed nordrimane sesquiterpene derivatives, salvirrane A-F (1-6), were isolated from the roots and rhizomes of Salvia castanea Diels f. tomentosa Stib. Comprehensive spectral analysis and a quantum chemical calculation strategy were employed to determine their structures.
View Article and Find Full Text PDFJ Org Chem
September 2024
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
(±)-Salvicatone A (), a C-meroterpenoid featuring a unique 6/6/6/6/6-pentacyclic carbon skeleton with a 7,8,8a,9,10,10a-hexahydropyren-1 ()-one motif, was isolated from the roots and rhizomes of Diels Stib. Its structure was characterized by comprehensive spectroscopic analyses along with computer-assisted structure elucidation, including ACD/structure elucidator and quantum chemical calculations with H/C NMR and electronic circular dichroism. Biogenetically, compound was constructed from decarboxylation following [4 + 2] Diels-Alder cycloaddition reaction between caffeic acid and miltirone analogue.
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