Dentifrices with different compositions are available on the market, but there is limited information about their properties. The aim of this in vitro study was to evaluate the physicochemical characteristics of 12 dentifrices divided into three categories, as containing desensitizing agents, Triclosan or whitening agents. Desiccation loss/residue analysis: 5 g of dentifrice was weighed five times for each group. pH analysis: 5 g of dentifrice were diluted in three parts of distilled water and analyzed using a digital potentiometer. Scanning electron microscopy (SEM): analysis of ashes, shape and size of the particles. Energy-dispersive x-ray spectroscopy (EDX): identification of the abrasive elements. Data were analyzed using ANOVA, Bonferroni post hoc test (α=0.05). Desiccation loss: 38.21% to 65.83%. Dentifrices containing Triclosan and desensitizing agents showed statistically significant differences among them (p<0.05). Whitening dentifrices showed statistically significant differences between Close-Up Whitening and Sensodyne Branqueador (44.72%, 65.83%, respectively). Most dentifrices presented neutral or basic pH. Different shape and size particles were observed in the SEM analysis. Abrasive elements were identified in the EDX. These results demonstrate that the evaluated dentifrices had different properties and their composition influences directly their characteristics, thus resulting in a more or less abrasive action on tooth surface. Knowing the characteristics of the dentifrices is important to indicate the ideal product for each case.
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http://dx.doi.org/10.1590/0103-6440201302209 | DOI Listing |
Cochrane Database Syst Rev
January 2025
Department of Otorhinolaryngology, Amsterdam University Medical Centre, Amsterdam, Netherlands.
Background: NSAID-exacerbated respiratory disease (N-ERD) is a hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, accompanied by chronic rhinosinusitis (with or without nasal polyps) or asthma. The prevalence of hypersensitivity to NSAIDs is estimated to be 2%. The first line of treatment is the avoidance of NSAIDs.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Department of Prosthodontics, RAK College of Dental Sciences, RAK Medical and Health Sciences University, Ras Al-Khaimah P.O. Box 12973, United Arab Emirates.
In-office teeth bleaching is an esthetic dental procedure performed to whiten teeth. A desensitizing procedure often requires prior in-office bleaching to relieve tooth hypersensitivity. The objective of this study was to evaluate the bleaching efficiency of teeth specimens pre-treated with different desensitizing agents by analyzing the color parameters.
View Article and Find Full Text PDFJ Clin Med
December 2024
Allergology Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
is a topoisomerase I inhibitor used for the treatment of various cancers, such as gastrointestinal, pancreatic, pulmonary, ovarian, and cervical cancers. Among chemotherapy agents, it represents a rare trigger of drug hypersensitivity reactions, with few cases being reported until today. We present the case of a patient with metastatic esophageal cancer and a history of -induced grade IV (WAO classification) anaphylaxis.
View Article and Find Full Text PDFSci Transl Med
January 2025
Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Front Pharmacol
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Key Laboratory of Saline-Alkali Vegetation Ecology Restoration, Ministry of Education, College of Life Science, Northeast Forestry University, Harbin, China.
Background: β-caryophyllene (BCP) is a naturally occurring bicyclic sesquiterpene extracted from various plants, and widely used as a medicinal agent for various diseases. During hepatocellular carcinoma (HCC) development, cancer cells generally exhibit increased cell proliferation due to mutations or aberrant expression of key regulatory genes. The current study determines the cytotoxic effects of BCP alone or in combination with doxorubicin (DOX) and cisplatin (DDP) on HCC cells, and elucidates the underlying mechanism of BCP to exert its anticancer activities.
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