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Prophylactic Use of Cardiac Medications and Survival in Duchenne Muscular Dystrophy.

Muscle Nerve

January 2025

Stead Family Department of Pediatrics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.

Introduction/aims: Prophylactic treatment of left ventricular dysfunction (LVD) in Duchenne muscular dystrophy (DMD) delays onset of LVD, but there is limited data showing impact on survival. Our aim was to describe survival among treated and untreated individuals with DMD.

Methods: Retrospective, population-based surveillance data from the Muscular Dystrophy Surveillance, Tracking and Research Network (MD STARnet) were used.

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Ecosystem-scale primary production may be proximately limited by nitrogen (N) but ultimately limited by phosphorus (P) because N fixation contributes new N that accumulates relative to P at ecosystem scales. However, the duration needed to transition between proximate N limitation and ultimate P limitation remains unknown for most ecosystems, including lakes. Here we present the results of a fully replicated, multi-annual lake mesocosm experiment that permitted full air-water-sediment interactions that mimicked lake ecosystem ecology.

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Atrazine causes serious contamination of agricultural soils and groundwater. This study investigated the influence mechanism of sterilized soil (CKs), unsterilized soil (CKn), sterilized soil amended with 45 (SsV1), 60 (SsV2), 75 (SsV3) days of vermicompost (the maturity days of vermicompost), and unsterilized soil amended with 45 (SnV1), 60 (SnV2), 75 (SnV3) days of vermicompost on atrazine catabolism. The atrazine degradation experiment lasted for 40 days.

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Maize is one of the major crops that are susceptible to infection and subsequent aflatoxin contamination, which poses a serious health threat to humans and domestic animals. Here, an RNA interference (RNAi) approach called Host-Induced Gene Silencing (HIGS) was employed to suppress the -methyl transferase gene (, also called ), a key gene involved in aflatoxin biosynthesis. An RNAi vector carrying part of the gene was introduced into the B104 maize line.

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Self-Normalized Moderate Deviations for Degenerate -Statistics.

Entropy (Basel)

January 2025

Department of Statistics and Data Science, Shenzhen International Center for Mathematics, Southern University of Science and Technology, Shenzhen 518055, China.

In this paper, we study self-normalized moderate deviations for degenerate -statistics of order 2. Let {Xi,i≥1} be i.i.

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