AI Article Synopsis
- Coated vesicle transport in cells occurs in yeast, mammals, and plants, utilizing three systems: COPI, COPII, and clathrin-coated vesicles (CCV) for moving proteins and lipids.
- Evidence suggests chloroplasts might have a similar vesicle transport system, potentially involving COPI and CCV-related proteins, alongside the identified COPII system.
- Bioinformatics research in Arabidopsis and rice identified some chloroplast proteins that could relate to COPI and CCV functions, but the COPII system appears to be the primary active transport mechanism in chloroplasts of these model plants.
Article Abstract
Coated vesicle transport occurs in the cytosol of yeast, mammals and plants. It consists of three different transport systems, the COPI, COPII and clathrin coated vesicles (CCV), all of which participate in the transfer of proteins and lipids between different cytosolic compartments. There are also indications that chloroplasts have a vesicle transport system. Several putative chloroplast-localized proteins, including CPSAR1 and CPRabA5e with similarities to cytosolic COPII transport-related proteins, were detected in previous experimental and bioinformatics studies. These indications raised the hypothesis that a COPI- and/or CCV-related system may be present in chloroplasts, in addition to a COPII-related system. To test this hypothesis we bioinformatically searched for chloroplast proteins that may have similar functions to known cytosolic COPI and CCV components in the model plants Arabidopsis thaliana and Oryza sativa (subsp. japonica) (rice). We found 29 such proteins, based on domain similarity, in Arabidopsis, and 14 in rice. However, many components could not be identified and among the identified most have assigned roles that are not related to either COPI or CCV transport. We conclude that COPII is probably the only active vesicle system in chloroplasts, at least in the model plants. The evolutionary implications of the findings are discussed.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138088 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104423 | PLOS |
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