Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids.

Antimicrob Agents Chemother

Service de Bactériologie, Centre National de Référence des Streptocoques, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, Assistance Publique Hôpitaux de Paris, Paris, France DHU Risques et Grossesse, Assistance Publique Hôpitaux de Paris, Paris, France INSERM, U1016, Institut Cochin, Paris, France CNRS (UMR 8104), Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France

Published: November 2014

Among 1,827 group B Streptococcus (GBS) strains collected between 2006 and 2013 by the French National Reference Center for Streptococci, 490 (26.8%) strains were erythromycin resistant. The erm(T) resistance gene was found in six strains belonging to capsular polysaccharides Ia, III, and V and was carried by the same mobilizable plasmid, which could be efficiently transferred by mobilization to GBS and Enterococcus faecalis recipients, thus promoting a broad dissemination of erm(T).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249376PMC
http://dx.doi.org/10.1128/AAC.03855-14DOI Listing

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