AI Article Synopsis
- Organ transplantation has saved over 500,000 lives in the past century, but it has led to an increase in secondary malignancies due to immunosuppressive treatments.
- Skin cancer is the most common type of cancer seen in organ transplant recipients and significantly impacts their health and survival.
- The authors examine the occurrence and types of skin cancer in these patients, highlight risk factors, and suggest management strategies and potential new treatments.
Article Abstract
During the past century, organ transplantation has delivered the miracle of life to more than 500,000 patients in need. Secondary malignancies have developed as an unforeseen consequence of intense immunosuppressive regimens. Cutaneous malignancies have been recognized as the most frequent cancer that arises post-transplantation. Among organ transplant recipients (OTRs), skin cancer is a substantial cause of morbidity and potential mortality. The authors discuss epidemiology and clinical presentation of cutaneous malignancies; associated risk factors; recommendation for the care of immunosuppressed OTRs, and emerging therapies on the horizon.
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