Objectives: To determine the association between hyperandrogenism and obesity with acne, and correlation between the severity of acne with the clinical and laboratory parameters of hyperandrogenism.
Methods: One hundred and forty-one female with acne vulgaris and 73 healthy women were included in this study. The correlation of clinical and laboratory signs of hyperandrogenism and the severity of acne was examined.
Results: The prevalence of overweight and obese individuals in the group with acne was determined significantly higher than the control group. There was a positive correlation between body mass index (BMI) value and the severity of acne. The frequency of hirsutism, menstrual irregularity, androgenetic alopecia, seborrhea and polycystic ovary in the group with acne were found significantly higher than the control group. The average levels of free testosterone (fT), total testosterone (TT), dehydroepiandrosteron sulfate, and prolactine in the groups with acne were found significantly higher compared with the control group. There was a positive correlation between the fT and TT levels and the severity of acne.
Conclusion: The prevalence of hyperandrogenism and obesity was increased in women with acne. According to the results of our study, it can be said that circulating androgen levels and BMI play a key role in the severity of acne.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris - Preliminary Study.
Clin Cosmet Investig Dermatol
January 2025
Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland.
Purpose: The aim was to quantitatively evaluate the effectiveness of LED light therapy combined with photoacceptor substances having anti-acne properties in reducing the symptoms of acne vulgaris.
Patients And Methods: 15 subjects aged 20 to 24 who suffered from moderate or severe acne lesions. The treatments were performed using a LED device (465-880 nm).
Real-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience.
Clin Cosmet Investig Dermatol
January 2025
Western University, London, ON, Canada.
Acne vulgaris is a globally prevalent dermatological condition associated with substantial physical and psychological burden. Although acne typically presents during adolescence, it is a chronic condition that also affects many adults. Despite the spectrum of treatments available for acne, limitations in tolerability and safety concerns can present challenges for the use of conventional medications in clinical practice.
View Article and Find Full Text PDFValidation of the Acne Core Outcomes Research Network Patient Global Assessment for Acne.
JAMA Dermatol
January 2025
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Clinical Epidemiology and Phenotypic Characteristics of Hidradenitis Suppurativa Disease in the Central Region of Saudi Arabia: Findings from a Cross-Sectional.
Clin Cosmet Investig Dermatol
January 2025
College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Background: Hidradenitis suppurativa (HS) is a complex condition that is often misdiagnosed, and regional data on its clinical features and risk factors are limited. This study aimed to explore the clinical epidemiology and phenotypic characteristics of HS in the central region of Saudi Arabia.
Materials And Methods: A cross-sectional study was conducted on HS patients at King Khalid University Hospital (KKUH) in Riyadh from December 2020 to December 2021.
A Multicentre Evaluation of a Ceramide-Containing Hydrating Cream-to-Foam Cleanser and Facial Moisturizing Lotion for Improving Topical Treatment Tolerability in Facial Acne.
J Cutan Med Surg
January 2025
Windsor Clinical Research, Windsor, ON, Canada.
Acne vulgaris (AV) is a common skin condition that can cause substantial psychosocial impact. Treatments of AV target clearing and prevention of lesions and reducing scarring and dyspigmentation. Numerous medications are used to target one or more of the pathogenetic factors contributing to AV.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!