One way to fix our broken system is to strengthen hospital-payer partnerships, which will help shift caregiver focus from volume to value.
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| http://dx.doi.org/10.1097/01.NUMA.0000453269.57887.05 | DOI Listing |
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Microglial activation states and their implications for Alzheimer's Disease.
J Prev Alzheimers Dis
January 2025
School of Health and Biomedical Sciences, RMIT University, 220 3-5 Plenty Road, Bundoora VIC 3082, Australia. Electronic address:
Alzheimer's Disease (AD) is a chronic neurodegenerative disorder characterized by the accumulation of toxic amyloid-beta (Aβ) plaques and neurofibrillary tangles (NFTs) of tau protein in the brain. Microglia, key immune cells of the central nervous system, play an important role in AD development and progression, primarily through their responses to Aβ and NFTs. Initially, microglia can clear Aβ, but in AD, chronic activation overwhelms protective mechanisms, leading to sustained neuroinflammation that enhances plaque toxicity, setting off a damaging cycle that affects neurons, astrocytes, cerebral vasculature, and other microglia.
View Article and Find Full Text PDFComparison of Performance, Egg Quality, and Egg Cost of Different Laying Genotypes in Free-Range System from 21 to 44 Weeks of Age.
Animals (Basel)
January 2025
Department of Agricultural Economics, Agriculture Faculty, Selçuk University, Konya 42130, Turkey.
The aim of this study was to compare the performance, egg quality and economic aspects of laying hybrids of different genotypes in free-range system. In the study, three different laying genotypes (Lohmann Brown, Lohmann Sandy and ATAK-S genotype) were used. Each group consisted of four replicates and each replicate contained 20 hens.
View Article and Find Full Text PDFMicrocapsule-Containing Self-Reporting Materials Based on Donor-acceptor Stenhouse Adducts.
ACS Macro Lett
January 2025
Department of Chemical Engineering, Key Laboratory of Advanced Materials (MOE), Tsinghua University, Beijing 100084, China.
The microcapsule-containing self-reporting system has attracted attention for its excellent characteristics in visualizing microdamage. In this study, we developed self-reporting materials based on the formation of donor-acceptor Stenhouse adducts (DASA) from microcapsules containing Meldrum's acid furfural conjugate (MAFC). Under mechanical force, MAFC is released from broken microcapsules and forms highly colored DASA with secondary amines in the matrix to indicate the small cracks or deformations.
View Article and Find Full Text PDFRaman signatures of inversion symmetry breaking structural transition in quasi-1D compound, (TaSe4)3I.
J Phys Condens Matter
January 2025
School of Physical Sciences, Indian Association for the Cultivation of Science, 2A & B Raja S C Mullick Road, Kolkata 700032, INDIA, Kolkata, 700032, INDIA.
The breaking of inversion symmetry combined with spin-orbit coupling, can give rise to intrigu- ing quantum phases and collective excitations. Here, we report systematic temperature dependent Raman scattering and theoretical calculations of phonon modes across the inversion symmetry- breaking structural transitions in a quasi-one-dimensional compound (TaSe4)3I. Our investigation revealed the emergence of three additional Raman-active modes in Raman spectra of the low- temperature (LT) non-centrosymmetric (NC) structure of the material.
View Article and Find Full Text PDFThe possible pathogenic mechanisms of microorganisms in infertility: a narrative review.
Arch Microbiol
January 2025
Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran.
Infertility can harm a patient in physical, psychological, spiritual, and medical ways. This illness is unusual because it affects the patient's companion and the patient individually. Infertility is a multifactorial disease, and various etiological factors like infection are known to develop this disorder.
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