Effective treatment of invasive Aspergillus fumigatus infection using combinations of topical and systemic antifungals in a severely burned patient.

J Burn Care Res

From the *Service of Pharmacy, ‡Service of Intensive Care Medicine, §Service of Plastic and Reconstructive Surgery, ‖Institute of Microbiology, ¶Service of Infectious Diseases, and #Service of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland; **Centre des Brûlés, Centre Hospitalier St. Joseph et St Luc, Lyon, France; and †School of Pharmaceutical Sciences, University of Geneva, University of Lausanne.

Published: November 2015

The authors describe an invasive Aspergillus fumigatus deep-burn wound infection in a severely burned patient that was successfully treated with a combination of topical terbinafine and systemic voriconazole antifungal therapy. To our knowledge, this is the first case report describing the effective control of an invasive deep-burn wound infection using this combination.

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Source
http://dx.doi.org/10.1097/BCR.0000000000000143DOI Listing

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